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Page 1
Centrosomal cohesion deficits as cellular biomarker in lymphoblastoid cell lines from LRRK2 Parkinson's disease patients.
Fernández B, Lara Ordóñez AJ, Fdez E, Mutez E, Comptdaer T, Leghay C, Kreisler A, Simonin C, Vandewynckel L, Defebvre L, Destée A, Bleuse S, Taymans JM, Chartier-Harlin MC, Hilfiker S. Fernández B, et al. Among authors: taymans jm. Biochem J. 2019 Oct 15;476(19):2797-2813. doi: 10.1042/BCJ20190315. Biochem J. 2019. PMID: 31527116 Free PMC article.
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites.
Greggio E, Taymans JM, Zhen EY, Ryder J, Vancraenenbroeck R, Beilina A, Sun P, Deng J, Jaffe H, Baekelandt V, Merchant K, Cookson MR. Greggio E, et al. Among authors: taymans jm. Biochem Biophys Res Commun. 2009 Nov 20;389(3):449-54. doi: 10.1016/j.bbrc.2009.08.163. Epub 2009 Sep 3. Biochem Biophys Res Commun. 2009. PMID: 19733152 Free PMC article.
The GTPase function of LRRK2.
Taymans JM. Taymans JM. Biochem Soc Trans. 2012 Oct;40(5):1063-9. doi: 10.1042/BST20120133. Biochem Soc Trans. 2012. PMID: 22988866 Review.
Phosphorylation of LRRK2: from kinase to substrate.
Lobbestael E, Baekelandt V, Taymans JM. Lobbestael E, et al. Among authors: taymans jm. Biochem Soc Trans. 2012 Oct;40(5):1102-10. doi: 10.1042/BST20120128. Biochem Soc Trans. 2012. PMID: 22988873 Review.
Regulation of LRRK2 by Phosphatases.
Taymans JM. Taymans JM. Adv Neurobiol. 2017;14:145-160. doi: 10.1007/978-3-319-49969-7_8. Adv Neurobiol. 2017. PMID: 28353283 Review.
GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.
Blanca Ramírez M, Lara Ordóñez AJ, Fdez E, Madero-Pérez J, Gonnelli A, Drouyer M, Chartier-Harlin MC, Taymans JM, Bubacco L, Greggio E, Hilfiker S. Blanca Ramírez M, et al. Among authors: taymans jm. Hum Mol Genet. 2017 Jul 15;26(14):2747-2767. doi: 10.1093/hmg/ddx161. Hum Mol Genet. 2017. PMID: 28453723 Free PMC article.
73 results