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299 results

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Page 1
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.
Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD. Sukhai MA, et al. Among authors: schimmer ad. J Clin Invest. 2013 Jan;123(1):315-28. doi: 10.1172/JCI64180. Epub 2012 Dec 3. J Clin Invest. 2013. PMID: 23202731 Free PMC article. Clinical Trial.
The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids.
Seneviratne AK, Xu M, Henao JJA, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, Mullokandov M, Sharon D, Thomas G, Chouinard-Watkins R, Hawley JR, Schafer C, Yau HL, Khuchua Z, Aman A, Al-Awar R, Gross A, Claypool SM, Bazinet RP, Lupien M, Chan S, De Carvalho DD, Minden MD, Bader GD, Stark KD, LeBlanc P, Schimmer AD. Seneviratne AK, et al. Among authors: schimmer ad. Cell Stem Cell. 2019 Apr 4;24(4):621-636.e16. doi: 10.1016/j.stem.2019.02.020. Epub 2019 Mar 28. Cell Stem Cell. 2019. PMID: 30930145 Free PMC article.
The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids.
Seneviratne AK, Xu M, Aristizabal Henao JJ, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, Mullokandov M, Sharon D, Thomas G, Chouinard-Watkins R, Hawley JR, Schafer C, Yau HL, Khuchua Z, Aman A, Al-Awar R, Gross A, Claypool SM, Bazinet RP, Lupien M, Chan S, De Carvalho DD, Minden MD, Bader GD, Stark KD, LeBlanc P, Schimmer AD. Seneviratne AK, et al. Among authors: schimmer ad. Cell Stem Cell. 2019 Jun 6;24(6):1007. doi: 10.1016/j.stem.2019.04.020. Cell Stem Cell. 2019. PMID: 31173706 Free article. No abstract available.
Phospholipid metabolism regulates AML growth and stemness.
Xu M, Seneviratne AK, Schimmer AD. Xu M, et al. Among authors: schimmer ad. Aging (Albany NY). 2019 Jun 25;11(12):3895-3897. doi: 10.18632/aging.102055. Aging (Albany NY). 2019. PMID: 31237862 Free PMC article. No abstract available.
Mitochondrial carrier homolog 2 is necessary for AML survival.
Khan DH, Mullokandov M, Wu Y, Voisin V, Gronda M, Hurren R, Wang X, MacLean N, Jeyaraju DV, Jitkova Y, Xu GW, Laister R, Seneviratne A, Blatman ZM, Ketela T, Bader GD, Marhon SA, De Carvalho DD, Minden MD, Gross A, Schimmer AD. Khan DH, et al. Among authors: schimmer ad. Blood. 2020 Jul 2;136(1):81-92. doi: 10.1182/blood.2019000106. Blood. 2020. PMID: 32299104 Free article.
Targeting neurolysin in acute myeloid leukemia.
Mirali S, Schimmer AD. Mirali S, et al. Among authors: schimmer ad. Mol Cell Oncol. 2020 May 23;7(4):1761243. doi: 10.1080/23723556.2020.1761243. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32944624 Free PMC article.
299 results