Hui E - Search Results

1

TCR-pMHC bond conformation controls TCR ligand discrimination.

Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J. Sasmal DK, et al. Among authors: hui e. Cell Mol Immunol. 2020 Mar;17(3):203-217. doi: 10.1038/s41423-019-0273-6. Epub 2019 Sep 17. Cell Mol Immunol. 2020. PMID: 31530899 Free PMC article.

2

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.

Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. Hui E, et al. Science. 2017 Mar 31;355(6332):1428-1433. doi: 10.1126/science.aaf1292. Epub 2017 Mar 9. Science. 2017. PMID: 28280247 Free PMC article.

3

Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.

Zhao Y, Harrison DL, Song Y, Ji J, Huang J, Hui E. Zhao Y, et al. Among authors: hui e. Cell Rep. 2018 Jul 10;24(2):379-390.e6. doi: 10.1016/j.celrep.2018.06.054. Cell Rep. 2018. PMID: 29996099 Free PMC article.

4

In vitro membrane reconstitution of the T-cell receptor proximal signaling network.

Hui E, Vale RD. Hui E, et al. Nat Struct Mol Biol. 2014 Feb;21(2):133-42. doi: 10.1038/nsmb.2762. Epub 2014 Jan 26. Nat Struct Mol Biol. 2014. PMID: 24463463 Free PMC article.

5

In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.

Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD. Carbone CB, et al. Among authors: hui e. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9338-E9345. doi: 10.1073/pnas.1710358114. Epub 2017 Oct 17. Proc Natl Acad Sci U S A. 2017. PMID: 29042512 Free PMC article.

6

Understanding T cell signaling using membrane reconstitution.

Hui E. Hui E. Immunol Rev. 2019 Sep;291(1):44-56. doi: 10.1111/imr.12767. Immunol Rev. 2019. PMID: 31402497 Review.

7

PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.

Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, Bennett EJ, Fu G, Hui E. Xu X, et al. Among authors: hui e. J Cell Biol. 2020 Jun 1;219(6):e201905085. doi: 10.1083/jcb.201905085. J Cell Biol. 2020. PMID: 32437509 Free PMC article.

8

Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy.

Wu W, Zhou Q, Masubuchi T, Shi X, Li H, Xu X, Huang M, Meng L, He X, Zhu H, Gao S, Zhang N, Jing R, Sun J, Wang H, Hui E, Wong CC, Xu C. Wu W, et al. Among authors: hui e. Cell. 2020 Aug 20;182(4):855-871.e23. doi: 10.1016/j.cell.2020.07.018. Epub 2020 Jul 29. Cell. 2020. PMID: 32730808 Free article.

9

Orientation-dependent CD45 inhibition with viral and engineered ligands.

Borowska MT, Liu LD, Caveney NA, Jude KM, Kim WJ, Masubuchi T, Hui E, Majzner RG, Garcia KC. Borowska MT, et al. Among authors: hui e. Sci Immunol. 2024 Oct 25;9(100):eadp0707. doi: 10.1126/sciimmunol.adp0707. Epub 2024 Oct 25. Sci Immunol. 2024. PMID: 39454026 Free PMC article.

10

Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors.

Xu X, Masubuchi T, Cai Q, Zhao Y, Hui E. Xu X, et al. Among authors: hui e. Elife. 2021 Nov 4;10:e74276. doi: 10.7554/eLife.74276. Elife. 2021. PMID: 34734802 Free PMC article.

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