O'Neill C - Search Results

1

The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P₃.

Furlong RM, Lindsay A, Anderson KE, Hawkins PT, Sullivan AM, O'Neill C. Furlong RM, et al. J Cell Sci. 2019 Oct 22;132(20):jcs233221. doi: 10.1242/jcs.233221. J Cell Sci. 2019. PMID: 31540955

2

Akt signal transduction dysfunction in Parkinson's disease.

Timmons S, Coakley MF, Moloney AM, O' Neill C. Timmons S, et al. Neurosci Lett. 2009 Dec 18;467(1):30-5. doi: 10.1016/j.neulet.2009.09.055. Epub 2009 Oct 1. Neurosci Lett. 2009. PMID: 19800394

3

PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease.

O' Neill C. O' Neill C. Exp Gerontol. 2013 Jul;48(7):647-53. doi: 10.1016/j.exger.2013.02.025. Epub 2013 Mar 5. Exp Gerontol. 2013. PMID: 23470275 Review.

4

The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes.

O'Flanagan CH, Morais VA, Wurst W, De Strooper B, O'Neill C. O'Flanagan CH, et al. Oncogene. 2015 Mar 12;34(11):1363-74. doi: 10.1038/onc.2014.81. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681957

5

PINK1 signalling in cancer biology.

O'Flanagan CH, O'Neill C. O'Flanagan CH, et al. Biochim Biophys Acta. 2014 Dec;1846(2):590-8. doi: 10.1016/j.bbcan.2014.10.006. Epub 2014 Oct 23. Biochim Biophys Acta. 2014. PMID: 25450579 Review.

6

Gut microbes metabolize Parkinson's disease drug.

O'Neill C. O'Neill C. Science. 2019 Jun 14;364(6445):1030-1031. doi: 10.1126/science.aax8937. Science. 2019. PMID: 31196998 No abstract available.

7

Nigral overexpression of α-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome.

O'Donovan SM, Crowley EK, Brown JR, O'Sullivan O, O'Leary OF, Timmons S, Nolan YM, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O'Neill C. O'Donovan SM, et al. Neurogastroenterol Motil. 2020 Jan;32(1):e13726. doi: 10.1111/nmo.13726. Epub 2019 Oct 2. Neurogastroenterol Motil. 2020. PMID: 31576631

8

Alterations in α-synuclein and PINK1 expression reduce neurite length and induce mitochondrial fission and Golgi fragmentation in midbrain neurons.

Furlong RM, O'Keeffe GW, O'Neill C, Sullivan AM. Furlong RM, et al. Neurosci Lett. 2020 Feb 16;720:134777. doi: 10.1016/j.neulet.2020.134777. Epub 2020 Jan 21. Neurosci Lett. 2020. PMID: 31978495 Free article.

9

Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease.

Stockdale SR, Draper LA, O'Donovan SM, Barton W, O'Sullivan O, Volpicelli-Daley LA, Sullivan AM, O'Neill C, Hill C. Stockdale SR, et al. Commun Biol. 2021 Sep 29;4(1):1140. doi: 10.1038/s42003-021-02666-1. Commun Biol. 2021. PMID: 34588600 Free PMC article.

10

The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system.

Somogyi A, Kirkham ED, Lloyd-Evans E, Winston J, Allen ND, Mackrill JJ, Anderson KE, Hawkins PT, Gardiner SE, Waller-Evans H, Sims R, Boland B, O'Neill C. Somogyi A, et al. J Cell Sci. 2023 Mar 15;136(6):jcs259875. doi: 10.1242/jcs.259875. Epub 2023 Mar 21. J Cell Sci. 2023. PMID: 36825945 Free PMC article.

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