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Page 1
Regulation of the endosomal SNX27-retromer by OTULIN.
Stangl A, Elliott PR, Pinto-Fernandez A, Bonham S, Harrison L, Schaub A, Kutzner K, Keusekotten K, Pfluger PT, El Oualid F, Kessler BM, Komander D, Krappmann D. Stangl A, et al. Among authors: bonham s. Nat Commun. 2019 Sep 20;10(1):4320. doi: 10.1038/s41467-019-12309-z. Nat Commun. 2019. PMID: 31541095 Free PMC article.
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Ghezraoui H, Oliveira C, Becker JR, Bilham K, Moralli D, Anzilotti C, Fischer R, Deobagkar-Lele M, Sanchiz-Calvo M, Fueyo-Marcos E, Bonham S, Kessler BM, Rottenberg S, Cornall RJ, Green CM, Chapman JR. Ghezraoui H, et al. Among authors: bonham s. Nature. 2018 Aug;560(7716):122-127. doi: 10.1038/s41586-018-0362-1. Epub 2018 Jul 25. Nature. 2018. PMID: 30046110 Free PMC article.
Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570: A Paradigmatic Example of Unspecific Protein Cross-linking with Michael Acceptor Motif-Containing Drugs.
Ward JA, Pinto-Fernandez A, Cornelissen L, Bonham S, Díaz-Sáez L, Riant O, Huber KVM, Kessler BM, Feron O, Tate EW. Ward JA, et al. Among authors: bonham s. J Med Chem. 2020 Apr 9;63(7):3756-3762. doi: 10.1021/acs.jmedchem.0c00144. Epub 2020 Mar 19. J Med Chem. 2020. PMID: 32109059 Free PMC article.
Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome.
van Leeuwen LL, Spraakman NA, Brat A, Huang H, Thorne AM, Bonham S, van Balkom BWM, Ploeg RJ, Kessler BM, Leuvenink HGD. van Leeuwen LL, et al. Among authors: bonham s. Transpl Int. 2021 Sep;34(9):1618-1629. doi: 10.1111/tri.13984. Transpl Int. 2021. PMID: 34448265 Free PMC article.
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
Ryzhakov G, Almuttaqi H, Corbin AL, Berthold DL, Khoyratty T, Eames HL, Bullers S, Pearson C, Ai Z, Zec K, Bonham S, Fischer R, Jostins-Dean L, Travis SPL, Kessler BM, Udalova IA. Ryzhakov G, et al. Among authors: bonham s. Nat Commun. 2021 Nov 18;12(1):6702. doi: 10.1038/s41467-021-27038-5. Nat Commun. 2021. PMID: 34795257 Free PMC article.
Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors.
Lo Faro ML, Rozenberg K, Huang H, Maslau S, Bonham S, Fischer R, Kessler B, Leuvenink H, Sharples E, Lindeman JH, Ploeg R. Lo Faro ML, et al. Among authors: bonham s. Kidney Int Rep. 2024 Feb 10;9(5):1473-1483. doi: 10.1016/j.ekir.2024.02.012. eCollection 2024 May. Kidney Int Rep. 2024. PMID: 38707804 Free PMC article.
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Vazquez-Rodriguez S, Wright M, Rogers CM, Cribbs AP, Velupillai S, Philpott M, Lee H, Dunford JE, Huber KVM, Robers MB, Vasta JD, Thezenas ML, Bonham S, Kessler B, Bennett J, Fedorov O, Raynaud F, Donovan A, Blagg J, Bavetsias V, Oppermann U, Bountra C, Kawamura A, Brennan PE. Vazquez-Rodriguez S, et al. Among authors: bonham s. Angew Chem Int Ed Engl. 2019 Jan 8;58(2):515-519. doi: 10.1002/anie.201810179. Epub 2018 Dec 7. Angew Chem Int Ed Engl. 2019. PMID: 30431220 Free PMC article.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: bonham s. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.
55 results