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Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Zaramela LS, Martino C, Alisson-Silva F, Rees SD, Diaz SL, Chuzel L, Ganatra MB, Taron CH, Secrest P, Zuñiga C, Huang J, Siegel D, Chang G, Varki A, Zengler K. Zaramela LS, et al. Among authors: secrest p. Nat Microbiol. 2019 Dec;4(12):2082-2089. doi: 10.1038/s41564-019-0564-9. Epub 2019 Sep 23. Nat Microbiol. 2019. PMID: 31548686 Free PMC article.
A red meat-derived glycan promotes inflammation and cancer progression.
Samraj AN, Pearce OM, Läubli H, Crittenden AN, Bergfeld AK, Banda K, Gregg CJ, Bingman AE, Secrest P, Diaz SL, Varki NM, Varki A. Samraj AN, et al. Among authors: secrest p. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):542-7. doi: 10.1073/pnas.1417508112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548184 Free PMC article.
Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome.
Srivastava S, Verhagen A, Sasmal A, Wasik BR, Diaz S, Yu H, Bensing BA, Khan N, Khedri Z, Secrest P, Sullam P, Varki N, Chen X, Parrish CR, Varki A. Srivastava S, et al. Among authors: secrest p. Glycobiology. 2022 Nov 22;32(12):1116-1136. doi: 10.1093/glycob/cwac050. Glycobiology. 2022. PMID: 35926090 Free PMC article.
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer.
Padler-Karavani V, Hurtado-Ziola N, Pu M, Yu H, Huang S, Muthana S, Chokhawala HA, Cao H, Secrest P, Friedmann-Morvinski D, Singer O, Ghaderi D, Verma IM, Liu YT, Messer K, Chen X, Varki A, Schwab R. Padler-Karavani V, et al. Among authors: secrest p. Cancer Res. 2011 May 1;71(9):3352-63. doi: 10.1158/0008-5472.CAN-10-4102. Epub 2011 Apr 19. Cancer Res. 2011. PMID: 21505105 Free PMC article.
Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer.
Läubli H, Pearce OM, Schwarz F, Siddiqui SS, Deng L, Stanczak MA, Deng L, Verhagen A, Secrest P, Lusk C, Schwartz AG, Varki NM, Bui JD, Varki A. Läubli H, et al. Among authors: secrest p. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14211-6. doi: 10.1073/pnas.1409580111. Epub 2014 Sep 15. Proc Natl Acad Sci U S A. 2014. PMID: 25225409 Free PMC article.
Siglec receptors impact mammalian lifespan by modulating oxidative stress.
Schwarz F, Pearce OM, Wang X, Samraj AN, Läubli H, Garcia JO, Lin H, Fu X, Garcia-Bingman A, Secrest P, Romanoski CE, Heyser C, Glass CK, Hazen SL, Varki N, Varki A, Gagneux P. Schwarz F, et al. Among authors: secrest p. Elife. 2015 Apr 7;4:e06184. doi: 10.7554/eLife.06184. Elife. 2015. PMID: 25846707 Free PMC article.
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