Guo C - Search Results

1

Novel HER2-Targeting Antibody-Drug Conjugates of Trastuzumab Beyond T-DM1 in Breast Cancer: Trastuzumab Deruxtecan(DS-8201a) and (Vic-)Trastuzumab Duocarmazine (SYD985).

Xu Z, Guo D, Jiang Z, Tong R, Jiang P, Bai L, Chen L, Zhu Y, Guo C, Shi J, Yu D. Xu Z, et al. Among authors: guo c, guo d. Eur J Med Chem. 2019 Dec 1;183:111682. doi: 10.1016/j.ejmech.2019.111682. Epub 2019 Sep 6. Eur J Med Chem. 2019. PMID: 31563805 Review.

2

Design, synthesis, cytotoxicity and mechanism of novel dihydroartemisinin-coumarin hybrids as potential anti-cancer agents.

Yu H, Hou Z, Tian Y, Mou Y, Guo C. Yu H, et al. Among authors: guo c. Eur J Med Chem. 2018 May 10;151:434-449. doi: 10.1016/j.ejmech.2018.04.005. Epub 2018 Apr 3. Eur J Med Chem. 2018. PMID: 29649740

3

Design, synthesis and biological evaluation of novel heptamethine cyanine dye-erlotinib conjugates as antitumor agents.

Yang X, Hou Z, Wang D, Mou Y, Guo C. Yang X, et al. Among authors: guo c. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127557. doi: 10.1016/j.bmcl.2020.127557. Epub 2020 Sep 16. Bioorg Med Chem Lett. 2020. PMID: 32949719

4

Lead optimization generates selenium-containing miconazole CYP51 inhibitors with improved pharmacological profile for the treatment of fungal infections.

Xu H, Yan ZZ, Guo MB, An R, Wang X, Zhang R, Mou YH, Hou Z, Guo C. Xu H, et al. Among authors: guo mb, guo c. Eur J Med Chem. 2021 Apr 15;216:113337. doi: 10.1016/j.ejmech.2021.113337. Epub 2021 Mar 2. Eur J Med Chem. 2021. PMID: 33713977

5

Design, synthesis, and structure-activity relationships of novel 6,7-disubstituted-4-phenoxyquinoline derivatives as potential antitumor agents.

Tang Q, Zhao Y, Du X, Chong L, Gong P, Guo C. Tang Q, et al. Among authors: guo c. Eur J Med Chem. 2013 Nov;69:77-89. doi: 10.1016/j.ejmech.2013.08.019. Epub 2013 Aug 19. Eur J Med Chem. 2013. PMID: 24012712

6

Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site.

Hou Z, Lin B, Bao Y, Yan HN, Zhang M, Chang XW, Zhang XX, Wang ZJ, Wei GF, Cheng MS, Liu Y, Guo C. Hou Z, et al. Among authors: guo c. Eur J Med Chem. 2017 May 26;132:1-10. doi: 10.1016/j.ejmech.2017.03.023. Epub 2017 Mar 16. Eur J Med Chem. 2017. PMID: 28334643

7

Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents.

Xu H, Su X, Guo MB, An R, Mou YH, Hou Z, Guo C. Xu H, et al. Among authors: guo mb, guo c. Eur J Med Chem. 2020 Jul 15;198:112360. doi: 10.1016/j.ejmech.2020.112360. Epub 2020 May 4. Eur J Med Chem. 2020. PMID: 32403018

8

Discovery of novel selenium-containing azole derivatives as antifungal agents by exploiting the hydrophobic cleft of CYP51.

Xu H, Mou YH, Guo MB, Zhang R, Yan ZZ, An R, Wang X, Su X, Hou Z, Guo C. Xu H, et al. Among authors: guo mb, guo c. Eur J Med Chem. 2022 Dec 5;243:114707. doi: 10.1016/j.ejmech.2022.114707. Epub 2022 Aug 28. Eur J Med Chem. 2022. PMID: 36057236

9

Discovery of Small-Molecule Autophagy Inhibitors by Disrupting the Protein-Protein Interactions Involving Autophagy-Related 5.

Xiang H, Liu R, Zhang X, An R, Zhou M, Tan C, Li Q, Su M, Guo C, Zhou L, Li Y, Wang R. Xiang H, et al. Among authors: guo c. J Med Chem. 2023 Feb 23;66(4):2457-2476. doi: 10.1021/acs.jmedchem.2c01233. Epub 2023 Feb 7. J Med Chem. 2023. PMID: 36749313

10

Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy.

Yuan Z, Chen S, Gao C, Dai Q, Zhang C, Sun Q, Lin JS, Guo C, Chen Y, Jiang Y. Yuan Z, et al. Among authors: guo c. Bioorg Chem. 2019 Jun;87:200-208. doi: 10.1016/j.bioorg.2019.03.027. Epub 2019 Mar 19. Bioorg Chem. 2019. PMID: 30901675

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