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Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy.
Faist B, Schlott F, Stemberger C, Dennehy KM, Krackhardt A, Verbeek M, Grigoleit GU, Schiemann M, Hoffmann D, Dick A, Martin K, Hildebrandt M, Busch DH, Neuenhahn M. Faist B, et al. Among authors: hildebrandt m. PLoS One. 2019 Sep 30;14(9):e0223258. doi: 10.1371/journal.pone.0223258. eCollection 2019. PLoS One. 2019. PMID: 31568490 Free PMC article.
Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.
Krackhardt AM, Anliker B, Hildebrandt M, Bachmann M, Eichmüller SB, Nettelbeck DM, Renner M, Uharek L, Willimsky G, Schmitt M, Wels WS, Schüssler-Lenz M. Krackhardt AM, et al. Among authors: hildebrandt m. Cancer Immunol Immunother. 2018 Apr;67(4):513-523. doi: 10.1007/s00262-018-2119-y. Epub 2018 Jan 29. Cancer Immunol Immunother. 2018. PMID: 29380009 Free PMC article. Review.
Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset.
Newman NJ, Yu-Wai-Man P, Carelli V, Moster ML, Biousse V, Vignal-Clermont C, Sergott RC, Klopstock T, Sadun AA, Barboni P, DeBusk AA, Girmens JF, Rudolph G, Karanjia R, Taiel M, Blouin L, Smits G, Katz B, Sahel JA; LHON Study Group. Newman NJ, et al. Ophthalmology. 2021 May;128(5):649-660. doi: 10.1016/j.ophtha.2020.12.012. Epub 2021 Jan 12. Ophthalmology. 2021. PMID: 33451738 Free article. Clinical Trial.
Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study.
Kokowski K, Stangl S, Seier S, Hildebrandt M, Vaupel P, Multhoff G. Kokowski K, et al. Among authors: hildebrandt m. Strahlenther Onkol. 2019 Apr;195(4):352-361. doi: 10.1007/s00066-019-01434-9. Epub 2019 Feb 11. Strahlenther Onkol. 2019. PMID: 30747241 Free PMC article. Clinical Trial.
Targeted Natural Killer Cell-Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial.
Multhoff G, Seier S, Stangl S, Sievert W, Shevtsov M, Werner C, Pockley AG, Blankenstein C, Hildebrandt M, Offner R, Ahrens N, Kokowski K, Hautmann M, Rödel C, Fietkau R, Lubgan D, Huber R, Hautmann H, Duell T, Molls M, Specht H, Haller B, Devecka M, Sauter A, Combs SE. Multhoff G, et al. Among authors: hildebrandt m. Clin Cancer Res. 2020 Oct 15;26(20):5368-5379. doi: 10.1158/1078-0432.CCR-20-1141. Epub 2020 Sep 1. Clin Cancer Res. 2020. PMID: 32873573 Clinical Trial.
Immunotherapy: opportunities, risks and future perspectives.
Hildebrandt M, Peggs K, Uharek L, Bollard CM, Heslop HE. Hildebrandt M, et al. Cytotherapy. 2014 Apr;16(4 Suppl):S120-9. doi: 10.1016/j.jcyt.2014.02.001. Cytotherapy. 2014. PMID: 24629797 Free PMC article. Review.
Regulation of advanced therapy medicinal products in Europe and the role of academia.
Pearce KF, Hildebrandt M, Greinix H, Scheding S, Koehl U, Worel N, Apperley J, Edinger M, Hauser A, Mischak-Weissinger E, Dickinson AM, Lowdell MW. Pearce KF, et al. Among authors: hildebrandt m. Cytotherapy. 2014 Mar;16(3):289-97. doi: 10.1016/j.jcyt.2013.08.003. Epub 2013 Oct 8. Cytotherapy. 2014. PMID: 24113428 Review.
Development of cell therapy medicinal products by academic institutes.
de Wilde S, Guchelaar HJ, Herberts C, Lowdell M, Hildebrandt M, Zandvliet M, Meij P. de Wilde S, et al. Among authors: hildebrandt m. Drug Discov Today. 2016 Aug;21(8):1206-12. doi: 10.1016/j.drudis.2016.04.016. Epub 2016 Apr 23. Drug Discov Today. 2016. PMID: 27117349
413 results