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LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses.
Sanchez David RY, Combredet C, Najburg V, Millot GA, Beauclair G, Schwikowski B, Léger T, Camadro JM, Jacob Y, Bellalou J, Jouvenet N, Tangy F, Komarova AV. Sanchez David RY, et al. Among authors: schwikowski b. Sci Signal. 2019 Oct 1;12(601):eaar3993. doi: 10.1126/scisignal.aar3993. Sci Signal. 2019. PMID: 31575732
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo.
Menegatti S, Guillemot V, Latis E, Yahia-Cherbal H, Mittermüller D, Rouilly V, Mascia E, Rosine N, Koturan S, Millot GA, Leloup C, Duffy D, Gleizes A, Hacein-Bey-Abina S; Milieu Intérieur Consortium; Sellam J, Berenbaum F, Miceli-Richard C, Dougados M, Bianchi E, Rogge L. Menegatti S, et al. Ann Rheum Dis. 2021 Apr;80(4):475-486. doi: 10.1136/annrheumdis-2020-218304. Epub 2020 Dec 2. Ann Rheum Dis. 2021. PMID: 33268443 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Variability of Primary Sjögren's Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.
Trutschel D, Bost P, Mariette X, Bondet V, Llibre A, Posseme C, Charbit B, Thorball CW, Jonsson R, Lessard CJ, Felten R, Ng WF, Chatenoud L, Dumortier H, Sibilia J, Fellay J, Brokstad KA, Appel S, Tarn JR, Quintana-Murci L, Mingueneau M, Meyer N, Duffy D, Schwikowski B, Gottenberg JE; Milieu Intérieur Consortium, ASSESS study investigators, and NECESSITY Consortium. Trutschel D, et al. Among authors: schwikowski b. Arthritis Rheumatol. 2022 Dec;74(12):1991-2002. doi: 10.1002/art.42265. Epub 2022 Nov 2. Arthritis Rheumatol. 2022. PMID: 35726083 Free PMC article.
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Posseme C, Llibre A, Charbit B, Bondet V, Rouilly V, Saint-André V, Boussier J, Bergstedt J, Smith N, Townsend L, Sugrue JA, Ní Cheallaigh C, Conlon N, Rotival M, Kobor MS, Mottez E, Pol S, Patin E, Albert ML, Quintana-Murci L, Duffy D; Milieu Intérieur Consortium. Posseme C, et al. Cell Rep. 2022 Jun 28;39(13):110989. doi: 10.1016/j.celrep.2022.110989. Cell Rep. 2022. PMID: 35767946 Free PMC article.
The immune factors driving DNA methylation variation in human blood.
Bergstedt J, Azzou SAK, Tsuo K, Jaquaniello A, Urrutia A, Rotival M, Lin DTS, MacIsaac JL, Kobor MS, Albert ML, Duffy D, Patin E, Quintana-Murci L; Milieu Intérieur Consortium. Bergstedt J, et al. Nat Commun. 2022 Oct 6;13(1):5895. doi: 10.1038/s41467-022-33511-6. Nat Commun. 2022. PMID: 36202838 Free PMC article.
Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection.
Duffy D, Nemes E, Llibre A, Rouilly V, Musvosvi M, Smith N, Filander E, Africa H, Mabwe S, Jaxa L, Charbit B, Mulenga H, Tameris M, Walzl G, Malherbe S, Thomas S, Hatherill M, Bilek N, Scriba TJ, Albert ML; Milieu Intérieur Consortium. Duffy D, et al. Clin Infect Dis. 2021 Nov 2;73(9):e3398-e3408. doi: 10.1093/cid/ciaa1562. Clin Infect Dis. 2021. PMID: 33059361 Free PMC article.
82 results