Kadurin I - Search Results

1

Disruption of the Key Ca²⁺ Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking.

Meyer JO, Dahimene S, Page KM, Ferron L, Kadurin I, Ellaway JIJ, Zhao P, Patel T, Rothwell SW, Lin P, Pratt WS, Dolphin AC. Meyer JO, et al. Among authors: kadurin i. Cell Rep. 2019 Oct 1;29(1):22-33.e5. doi: 10.1016/j.celrep.2019.08.079. Cell Rep. 2019. PMID: 31577951 Free PMC article.

2

A new look at calcium channel α2δ subunits.

Bauer CS, Tran-Van-Minh A, Kadurin I, Dolphin AC. Bauer CS, et al. Among authors: kadurin i. Curr Opin Neurobiol. 2010 Oct;20(5):563-71. doi: 10.1016/j.conb.2010.05.007. Epub 2010 Jun 25. Curr Opin Neurobiol. 2010. PMID: 20579869 Review.

3

Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.

Cassidy JS, Ferron L, Kadurin I, Pratt WS, Dolphin AC. Cassidy JS, et al. Among authors: kadurin i. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8979-84. doi: 10.1073/pnas.1403731111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889613 Free PMC article.

4

Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.

Lana B, Page KM, Kadurin I, Ho S, Nieto-Rostro M, Dolphin AC. Lana B, et al. Among authors: kadurin i. Sci Rep. 2016 Apr 14;6:24531. doi: 10.1038/srep24531. Sci Rep. 2016. PMID: 27076051 Free PMC article.

5

Proteolytic maturation of α₂δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.

Kadurin I, Ferron L, Rothwell SW, Meyer JO, Douglas LR, Bauer CS, Lana B, Margas W, Alexopoulos O, Nieto-Rostro M, Pratt WS, Dolphin AC. Kadurin I, et al. Elife. 2016 Oct 26;5:e21143. doi: 10.7554/eLife.21143. Elife. 2016. PMID: 27782881 Free PMC article.

6

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α₂δ-1 subunit.

Kadurin I, Rothwell SW, Lana B, Nieto-Rostro M, Dolphin AC. Kadurin I, et al. Sci Rep. 2017 Mar 3;7:43802. doi: 10.1038/srep43802. Sci Rep. 2017. PMID: 28256585 Free PMC article.

7

Proteolytic maturation of α₂δ controls the probability of synaptic vesicular release.

Ferron L, Kadurin I, Dolphin AC. Ferron L, et al. Among authors: kadurin i. Elife. 2018 Jun 19;7:e37507. doi: 10.7554/eLife.37507. Elife. 2018. PMID: 29916807 Free PMC article.

8

The α₂δ-like Protein Cachd1 Increases N-type Calcium Currents and Cell Surface Expression and Competes with α₂δ-1.

Dahimene S, Page KM, Kadurin I, Ferron L, Ho DY, Powell GT, Pratt WS, Wilson SW, Dolphin AC. Dahimene S, et al. Among authors: kadurin i. Cell Rep. 2018 Nov 6;25(6):1610-1621.e5. doi: 10.1016/j.celrep.2018.10.033. Cell Rep. 2018. PMID: 30404013 Free PMC article.

9

The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function.

Davies A, Kadurin I, Alvarez-Laviada A, Douglas L, Nieto-Rostro M, Bauer CS, Pratt WS, Dolphin AC. Davies A, et al. Among authors: kadurin i. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1654-9. doi: 10.1073/pnas.0908735107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080692 Free PMC article.

10

The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin.

Bauer CS, Nieto-Rostro M, Rahman W, Tran-Van-Minh A, Ferron L, Douglas L, Kadurin I, Sri Ranjan Y, Fernandez-Alacid L, Millar NS, Dickenson AH, Lujan R, Dolphin AC. Bauer CS, et al. Among authors: kadurin i. J Neurosci. 2009 Apr 1;29(13):4076-88. doi: 10.1523/JNEUROSCI.0356-09.2009. J Neurosci. 2009. PMID: 19339603 Free PMC article.

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