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Detecting and Characterizing the Kinetic Activation of Thermal Networks in Proteins: Thermal Transfer from a Distal, Solvent-Exposed Loop to the Active Site in Soybean Lipoxygenase.
Zaragoza JPT, Nguy A, Minnetian N, Deng Z, Iavarone AT, Offenbacher AR, Klinman JP. Zaragoza JPT, et al. Among authors: offenbacher ar. J Phys Chem B. 2019 Oct 17;123(41):8662-8674. doi: 10.1021/acs.jpcb.9b07228. Epub 2019 Oct 3. J Phys Chem B. 2019. PMID: 31580070 Free PMC article.
Synthesis of Site-Specifically 13C Labeled Linoleic Acids.
Offenbacher AR, Zhu H, Klinman JP. Offenbacher AR, et al. Tetrahedron Lett. 2016 Oct 12;57(41):4537-4540. doi: 10.1016/j.tetlet.2016.08.071. Epub 2016 Aug 22. Tetrahedron Lett. 2016. PMID: 28260819 Free PMC article.
Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.
Offenbacher AR, Hu S, Poss EM, Carr CAM, Scouras AD, Prigozhin DM, Iavarone AT, Palla A, Alber T, Fraser JS, Klinman JP. Offenbacher AR, et al. ACS Cent Sci. 2017 Jun 28;3(6):570-579. doi: 10.1021/acscentsci.7b00142. Epub 2017 Jun 9. ACS Cent Sci. 2017. PMID: 28691068 Free PMC article.
Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
Hu S, Offenbacher AR, Thompson EM, Gee CL, Wilcoxen J, Carr CAM, Prigozhin DM, Yang V, Alber T, Britt RD, Fraser JS, Klinman JP. Hu S, et al. Among authors: offenbacher ar. J Am Chem Soc. 2019 Jan 30;141(4):1555-1567. doi: 10.1021/jacs.8b10992. Epub 2019 Jan 15. J Am Chem Soc. 2019. PMID: 30645119 Free PMC article.
43 results