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Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.
Kurimchak AM, Herrera-Montávez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Kurimchak AM, et al. Among authors: peri s. Sci Signal. 2020 Feb 18;13(619):eaax8238. doi: 10.1126/scisignal.aax8238. Sci Signal. 2020. PMID: 32071169 Free PMC article.
Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models.
Kukuyan AM, Sementino E, Kadariya Y, Menges CW, Cheung M, Tan Y, Cai KQ, Slifker MJ, Peri S, Klein-Szanto AJ, Rauscher FJ 3rd, Testa JR. Kukuyan AM, et al. Among authors: peri s. Cancer Res. 2019 Aug 15;79(16):4113-4123. doi: 10.1158/0008-5472.CAN-18-4093. Epub 2019 May 31. Cancer Res. 2019. PMID: 31151962 Free PMC article.
NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Cheng Y, Liao S, Xu G, Hu J, Guo D, Du F, Contreras A, Cai KQ, Peri S, Wang Y, Corney DC, Noronha AM, Chau LQ, Zhou G, Wiest DL, Bellacosa A, Wechsler-Reya RJ, Zhao Y, Yang ZJ. Cheng Y, et al. Among authors: peri s. Cell Rep. 2020 Jun 23;31(12):107782. doi: 10.1016/j.celrep.2020.107782. Cell Rep. 2020. PMID: 32579914 Free PMC article.
Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma.
Tan Y, Sementino E, Cheung M, Peri S, Menges CW, Kukuyan AM, Zhang T, Khazak V, Fox LA, Ross EA, Ramanathan S, Jhanwar SC, Flores RM, Balachandran S, Testa JR. Tan Y, et al. Among authors: peri s. Clin Cancer Res. 2021 Feb 15;27(4):1200-1213. doi: 10.1158/1078-0432.CCR-18-3683. Epub 2020 Nov 17. Clin Cancer Res. 2021. PMID: 33203643 Free PMC article.
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Sementino E, et al. Among authors: peri s. Mol Cancer Res. 2022 May 4;20(5):699-711. doi: 10.1158/1541-7786.MCR-21-0837. Mol Cancer Res. 2022. PMID: 35082167 Free PMC article.
152 results