Cleary ML - Search Results

1

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells.

Jeong J, Jager A, Domizi P, Pavel-Dinu M, Gojenola L, Iwasaki M, Wei MC, Pan F, Zehnder JL, Porteus MH, Davis KL, Cleary ML. Jeong J, et al. Among authors: cleary ml. Blood Adv. 2019 Oct 8;3(19):2825-2835. doi: 10.1182/bloodadvances.2019000450. Blood Adv. 2019. PMID: 31582391 Free PMC article.

2

MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.

Buechele C, Breese EH, Schneidawind D, Lin CH, Jeong J, Duque-Afonso J, Wong SH, Smith KS, Negrin RS, Porteus M, Cleary ML. Buechele C, et al. Among authors: cleary ml. Blood. 2015 Oct 1;126(14):1683-94. doi: 10.1182/blood-2015-05-646398. Epub 2015 Aug 26. Blood. 2015. PMID: 26311362 Free PMC article.

3

Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.

Breese EH, Buechele C, Dawson C, Cleary ML, Porteus MH. Breese EH, et al. Among authors: cleary ml. PLoS One. 2015 Sep 9;10(9):e0136644. doi: 10.1371/journal.pone.0136644. eCollection 2015. PLoS One. 2015. PMID: 26351841 Free PMC article.

4

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing.

Schneidawind C, Jeong J, Schneidawind D, Kim IS, Duque-Afonso J, Wong SHK, Iwasaki M, Breese EH, Zehnder JL, Porteus M, Cleary ML. Schneidawind C, et al. Among authors: cleary ml. Blood Adv. 2018 Apr 24;2(8):832-845. doi: 10.1182/bloodadvances.2017013748. Blood Adv. 2018. PMID: 29650777 Free PMC article.

5

Novel methods and approaches to acute lymphoblastic leukemia drug discovery.

Wei MC, Cleary ML. Wei MC, et al. Among authors: cleary ml. Expert Opin Drug Discov. 2014 Dec;9(12):1435-46. doi: 10.1517/17460441.2014.956720. Epub 2014 Sep 12. Expert Opin Drug Discov. 2014. PMID: 25212992 Review.

6

CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.

Iwasaki M, Liedtke M, Gentles AJ, Cleary ML. Iwasaki M, et al. Among authors: cleary ml. Cell Stem Cell. 2015 Oct 1;17(4):412-21. doi: 10.1016/j.stem.2015.08.008. Epub 2015 Sep 18. Cell Stem Cell. 2015. PMID: 26387756 Free PMC article.

7

SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression.

Lin CH, Wong SH, Kurzer JH, Schneidawind C, Wei MC, Duque-Afonso J, Jeong J, Feng X, Cleary ML. Lin CH, et al. Among authors: cleary ml. Cell Rep. 2018 Apr 24;23(4):1166-1177. doi: 10.1016/j.celrep.2018.03.124. Cell Rep. 2018. PMID: 29694893 Free PMC article.

8

GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis.

Wang Z, Iwasaki M, Ficara F, Lin C, Matheny C, Wong SH, Smith KS, Cleary ML. Wang Z, et al. Among authors: cleary ml. Cancer Cell. 2010 Jun 15;17(6):597-608. doi: 10.1016/j.ccr.2010.04.024. Cancer Cell. 2010. PMID: 20541704 Free PMC article.

9

The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.

Wong SH, Goode DL, Iwasaki M, Wei MC, Kuo HP, Zhu L, Schneidawind D, Duque-Afonso J, Weng Z, Cleary ML. Wong SH, et al. Among authors: cleary ml. Cancer Cell. 2015 Aug 10;28(2):198-209. doi: 10.1016/j.ccell.2015.06.003. Epub 2015 Jul 16. Cancer Cell. 2015. PMID: 26190263 Free PMC article.

10

Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML. Wong P, et al. Among authors: cleary ml. Genes Dev. 2007 Nov 1;21(21):2762-74. doi: 10.1101/gad.1602107. Epub 2007 Oct 17. Genes Dev. 2007. PMID: 17942707 Free PMC article.

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