Salvador JAR - Search Results

1

Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity.

Pinto P, Machado CM, Moreira J, Almeida JDP, Silva PMA, Henriques AC, Soares JX, Salvador JAR, Afonso C, Pinto M, Bousbaa H, Cidade H. Pinto P, et al. Among authors: salvador jar. Eur J Med Chem. 2019 Dec 15;184:111752. doi: 10.1016/j.ejmech.2019.111752. Epub 2019 Oct 3. Eur J Med Chem. 2019. PMID: 31610374

2

Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors.

Moreira VM, Vasaitis TS, Njar VC, Salvador JA. Moreira VM, et al. Steroids. 2007 Dec;72(14):939-48. doi: 10.1016/j.steroids.2007.08.004. Epub 2007 Aug 15. Steroids. 2007. PMID: 17884122

3

Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity.

Santos RC, Salvador JA, Marín S, Cascante M. Santos RC, et al. Bioorg Med Chem. 2009 Sep 1;17(17):6241-50. doi: 10.1016/j.bmc.2009.07.050. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19674909 Free article.

4

Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.

Santos RC, Salvador JA, Marín S, Cascante M, Moreira JN, Dinis TC. Santos RC, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4385-96. doi: 10.1016/j.bmc.2010.04.085. Epub 2010 Apr 29. Bioorg Med Chem. 2010. PMID: 20494586

5

Bismuth compounds in medicinal chemistry.

Salvador JA, Figueiredo SA, Pinto RM, Silvestre SM. Salvador JA, et al. Future Med Chem. 2012 Jul;4(11):1495-523. doi: 10.4155/fmc.12.95. Future Med Chem. 2012. PMID: 22857536 Review.

6

Synthesis of novel ursolic acid heterocyclic derivatives with improved abilities of antiproliferation and induction of p53, p21waf1 and NOXA in pancreatic cancer cells.

Leal AS, Wang R, Salvador JA, Jing Y. Leal AS, et al. Bioorg Med Chem. 2012 Oct 1;20(19):5774-86. doi: 10.1016/j.bmc.2012.08.010. Epub 2012 Aug 16. Bioorg Med Chem. 2012. PMID: 22959527

7

Synthesis of novel heterocyclic oleanolic acid derivatives with improved antiproliferative activity in solid tumor cells.

Leal AS, Wang R, Salvador JA, Jing Y. Leal AS, et al. Org Biomol Chem. 2013 Feb 13;11(10):1726-38. doi: 10.1039/c3ob00011g. Org Biomol Chem. 2013. PMID: 23381885

8

Novel oleanolic vinyl boronates: synthesis and antitumor activity.

Moreira VM, Salvador JA, Simões S, Destro F, Gavioli R. Moreira VM, et al. Eur J Med Chem. 2013 May;63:46-56. doi: 10.1016/j.ejmech.2013.01.040. Epub 2013 Feb 9. Eur J Med Chem. 2013. PMID: 23455056

9

Synthesis and anticancer activity of novel fluorinated asiatic acid derivatives.

Gonçalves BM, Salvador JA, Marín S, Cascante M. Gonçalves BM, et al. Eur J Med Chem. 2016 May 23;114:101-17. doi: 10.1016/j.ejmech.2016.02.057. Epub 2016 Mar 22. Eur J Med Chem. 2016. PMID: 26974379

10

Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells.

Mendes VIS, Bartholomeusz GA, Ayres M, Gandhi V, Salvador JAR. Mendes VIS, et al. Among authors: salvador jar. Eur J Med Chem. 2016 Nov 10;123:317-331. doi: 10.1016/j.ejmech.2016.07.045. Epub 2016 Jul 22. Eur J Med Chem. 2016. PMID: 27484517 Free PMC article.

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