Shilatifard A - Search Results

1

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.

LeRoy G, Oksuz O, Descostes N, Aoi Y, Ganai RA, Kara HO, Yu JR, Lee CH, Stafford J, Shilatifard A, Reinberg D. LeRoy G, et al. Among authors: shilatifard a. Sci Adv. 2019 Oct 2;5(10):eaay3068. doi: 10.1126/sciadv.aay3068. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31616795 Free PMC article.

2

Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.

Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A, Reinberg D. Pavri R, et al. Among authors: shilatifard a. Cell. 2006 May 19;125(4):703-17. doi: 10.1016/j.cell.2006.04.029. Cell. 2006. PMID: 16713563 Free article.

3

PAF1 regulation of promoter-proximal pause release via enhancer activation.

Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. Chen FX, et al. Among authors: shilatifard a. Science. 2017 Sep 22;357(6357):1294-1298. doi: 10.1126/science.aan3269. Epub 2017 Aug 31. Science. 2017. PMID: 28860207 Free PMC article.

4

Promoter bivalency favors an open chromatin architecture in embryonic stem cells.

Mas G, Blanco E, Ballaré C, Sansó M, Spill YG, Hu D, Aoi Y, Le Dily F, Shilatifard A, Marti-Renom MA, Di Croce L. Mas G, et al. Among authors: shilatifard a. Nat Genet. 2018 Oct;50(10):1452-1462. doi: 10.1038/s41588-018-0218-5. Epub 2018 Sep 17. Nat Genet. 2018. PMID: 30224650

5

Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy.

Liang K, Smith ER, Aoi Y, Stoltz KL, Katagi H, Woodfin AR, Rendleman EJ, Marshall SA, Murray DC, Wang L, Ozark PA, Mishra RK, Hashizume R, Schiltz GE, Shilatifard A. Liang K, et al. Among authors: shilatifard a. Cell. 2018 Oct 18;175(3):766-779.e17. doi: 10.1016/j.cell.2018.09.027. Cell. 2018. PMID: 30340042 Free PMC article.

6

NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release.

Aoi Y, Smith ER, Shah AP, Rendleman EJ, Marshall SA, Woodfin AR, Chen FX, Shiekhattar R, Shilatifard A. Aoi Y, et al. Among authors: shilatifard a. Mol Cell. 2020 Apr 16;78(2):261-274.e5. doi: 10.1016/j.molcel.2020.02.014. Epub 2020 Mar 9. Mol Cell. 2020. PMID: 32155413 Free PMC article.

7

The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts.

Beckedorff F, Blumenthal E, daSilva LF, Aoi Y, Cingaram PR, Yue J, Zhang A, Dokaneheifard S, Valencia MG, Gaidosh G, Shilatifard A, Shiekhattar R. Beckedorff F, et al. Among authors: shilatifard a. Cell Rep. 2020 Jul 21;32(3):107917. doi: 10.1016/j.celrep.2020.107917. Cell Rep. 2020. PMID: 32697989 Free PMC article.

8

DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.

Cao K, Ugarenko M, Ozark PA, Wang J, Marshall SA, Rendleman EJ, Liang K, Wang L, Zou L, Smith ER, Yue F, Shilatifard A. Cao K, et al. Among authors: shilatifard a. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27365-27373. doi: 10.1073/pnas.2001075117. Epub 2020 Oct 19. Proc Natl Acad Sci U S A. 2020. PMID: 33077595 Free PMC article.

9

Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression.

Zheng B, Aoi Y, Shah AP, Iwanaszko M, Das S, Rendleman EJ, Zha D, Khan N, Smith ER, Shilatifard A. Zheng B, et al. Among authors: shilatifard a. Genes Dev. 2021 Feb 1;35(3-4):273-285. doi: 10.1101/gad.346106.120. Epub 2021 Jan 14. Genes Dev. 2021. PMID: 33446572 Free PMC article.

10

Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma.

Katagi H, Takata N, Aoi Y, Zhang Y, Rendleman EJ, Blyth GT, Eckerdt FD, Tomita Y, Sasaki T, Saratsis AM, Kondo A, Goldman S, Becher OJ, Smith E, Zou L, Shilatifard A, Hashizume R. Katagi H, et al. Among authors: shilatifard a. Neuro Oncol. 2021 Aug 2;23(8):1348-1359. doi: 10.1093/neuonc/noab009. Neuro Oncol. 2021. PMID: 33471107 Free PMC article.

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