Freeland A - Search Results

1

A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.

Yin M, Baslan T, Walker RL, Zhu YJ, Freeland A, Matsukawa T, Sridharan S, Nussenzweig A, Pruitt SC, Lowe SW, Meltzer PS, Aplan PD. Yin M, et al. Among authors: freeland a. JCI Insight. 2019 Dec 5;4(23):e131434. doi: 10.1172/jci.insight.131434. JCI Insight. 2019. PMID: 31622281 Free PMC article.

2

Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.

Matsukawa T, Yin M, Baslan T, Chung YJ, Cao D, Bertoli R, Zhu YJ, Walker RL, Freeland A, Knudsen E, Lowe SW, Meltzer PS, Aplan PD. Matsukawa T, et al. Among authors: freeland a. FASEB J. 2022 Sep;36(9):e22430. doi: 10.1096/fj.202200061RR. FASEB J. 2022. PMID: 35920299 Free PMC article.

3

DNA damage response and tumorigenesis in Mcm2-deficient mice.

Kunnev D, Rusiniak ME, Kudla A, Freeland A, Cady GK, Pruitt SC. Kunnev D, et al. Among authors: freeland a. Oncogene. 2010 Jun 24;29(25):3630-8. doi: 10.1038/onc.2010.125. Epub 2010 May 3. Oncogene. 2010. PMID: 20440269 Free PMC article.

4

Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.

Rusiniak ME, Kunnev D, Freeland A, Cady GK, Pruitt SC. Rusiniak ME, et al. Among authors: freeland a. Oncogene. 2012 Sep 6;31(36):4034-44. doi: 10.1038/onc.2011.566. Epub 2011 Dec 12. Oncogene. 2012. PMID: 22158038 Free PMC article.

5

Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer.

Pruitt SC, Bailey KJ, Freeland A. Pruitt SC, et al. Among authors: freeland a. Stem Cells. 2007 Dec;25(12):3121-32. doi: 10.1634/stemcells.2007-0483. Epub 2007 Aug 23. Stem Cells. 2007. PMID: 17717065

6

Cell cycle heterogeneity in the small intestinal crypt and maintenance of genome integrity.

Pruitt SC, Freeland A, Kudla A. Pruitt SC, et al. Among authors: freeland a. Stem Cells. 2010 Jul;28(7):1250-9. doi: 10.1002/stem.450. Stem Cells. 2010. PMID: 20503265 Free PMC article.

7

Effect of minichromosome maintenance protein 2 deficiency on the locations of DNA replication origins.

Kunnev D, Freeland A, Qin M, Leach RW, Wang J, Shenoy RM, Pruitt SC. Kunnev D, et al. Among authors: freeland a. Genome Res. 2015 Apr;25(4):558-69. doi: 10.1101/gr.176099.114. Epub 2015 Mar 11. Genome Res. 2015. PMID: 25762552 Free PMC article.

8

A Signature of Genomic Instability Resulting from Deficient Replication Licensing.

Pruitt SC, Qin M, Wang J, Kunnev D, Freeland A. Pruitt SC, et al. Among authors: freeland a. PLoS Genet. 2017 Jan 3;13(1):e1006547. doi: 10.1371/journal.pgen.1006547. eCollection 2017 Jan. PLoS Genet. 2017. PMID: 28045896 Free PMC article.

9

DNA replication stress restricts ribosomal DNA copy number.

Salim D, Bradford WD, Freeland A, Cady G, Wang J, Pruitt SC, Gerton JL. Salim D, et al. Among authors: freeland a. PLoS Genet. 2017 Sep 15;13(9):e1007006. doi: 10.1371/journal.pgen.1007006. eCollection 2017 Sep. PLoS Genet. 2017. PMID: 28915237 Free PMC article.

10

Stem/progenitor cell-specific enhanced green fluorescent protein expression driven by the endogenous Mcm2 promoter.

Maslov AY, Bailey KJ, Mielnicki LM, Freeland AL, Sun X, Burhans WC, Pruitt SC. Maslov AY, et al. Stem Cells. 2007 Jan;25(1):132-8. doi: 10.1634/stemcells.2006-0032. Epub 2006 Sep 28. Stem Cells. 2007. PMID: 17008428

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