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Page 1
Antitubercular Triazines: Optimization and Intrabacterial Metabolism.
Wang X, Inoyama D, Russo R, Li SG, Jadhav R, Stratton TP, Mittal N, Bilotta JA, Singleton E, Kim T, Paget SD, Pottorf RS, Ahn YM, Davila-Pagan A, Kandasamy S, Grady C, Hussain S, Soteropoulos P, Zimmerman MD, Ho HP, Park S, Dartois V, Ekins S, Connell N, Kumar P, Freundlich JS. Wang X, et al. Among authors: stratton tp. Cell Chem Biol. 2020 Feb 20;27(2):172-185.e11. doi: 10.1016/j.chembiol.2019.10.010. Epub 2019 Nov 8. Cell Chem Biol. 2020. PMID: 31711854 Free PMC article.
Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug Discovery.
Ekins S, Madrid PB, Sarker M, Li SG, Mittal N, Kumar P, Wang X, Stratton TP, Zimmerman M, Talcott C, Bourbon P, Travers M, Yadav M, Freundlich JS. Ekins S, et al. Among authors: stratton tp. PLoS One. 2015 Oct 30;10(10):e0141076. doi: 10.1371/journal.pone.0141076. eCollection 2015. PLoS One. 2015. PMID: 26517557 Free PMC article.
Addressing the Metabolic Stability of Antituberculars through Machine Learning.
Stratton TP, Perryman AL, Vilchèze C, Russo R, Li SG, Patel JS, Singleton E, Ekins S, Connell N, Jacobs WR Jr, Freundlich JS. Stratton TP, et al. ACS Med Chem Lett. 2017 Sep 14;8(10):1099-1104. doi: 10.1021/acsmedchemlett.7b00299. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057058 Free PMC article.
Open drug discovery for the Zika virus.
Ekins S, Mietchen D, Coffee M, Stratton TP, Freundlich JS, Freitas-Junior L, Muratov E, Siqueira-Neto J, Williams AJ, Andrade C. Ekins S, et al. Among authors: stratton tp. F1000Res. 2016 Feb 9;5:150. doi: 10.12688/f1000research.8013.1. eCollection 2016. F1000Res. 2016. PMID: 27134728 Free PMC article.
Concise Total Synthesis of Herqulines B and C.
He C, Stratton TP, Baran PS. He C, et al. Among authors: stratton tp. J Am Chem Soc. 2019 Jan 9;141(1):29-32. doi: 10.1021/jacs.8b13029. Epub 2018 Dec 24. J Am Chem Soc. 2019. PMID: 30575396 Free PMC article.
Ideality in Context: Motivations for Total Synthesis.
Peters DS, Pitts CR, McClymont KS, Stratton TP, Bi C, Baran PS. Peters DS, et al. Among authors: stratton tp. Acc Chem Res. 2021 Feb 2;54(3):605-617. doi: 10.1021/acs.accounts.0c00821. Epub 2021 Jan 21. Acc Chem Res. 2021. PMID: 33476518 Free PMC article.
Total Synthesis of Tagetitoxin.
He C, Chu H, Stratton TP, Kossler D, Eberle KJ, Flood DT, Baran PS. He C, et al. Among authors: stratton tp. J Am Chem Soc. 2020 Aug 12;142(32):13683-13688. doi: 10.1021/jacs.0c06641. Epub 2020 Jul 27. J Am Chem Soc. 2020. PMID: 32687336 Free PMC article.
45 results