Murray SJ - Search Results

1

Efficacy of dual intracerebroventricular and intravitreal CLN5 gene therapy in sheep prompts the first clinical trial to treat CLN5 Batten disease.

Murray SJ, Wellby MP, Barrell GK, Russell KN, Deane AR, Wynyard JR, Gray SJ, Palmer DN, Mitchell NL. Murray SJ, et al. Front Pharmacol. 2023 Oct 24;14:1212235. doi: 10.3389/fphar.2023.1212235. eCollection 2023. Front Pharmacol. 2023. PMID: 37942487 Free PMC article.

2

Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease.

Mitchell NL, Murray SJ, Wellby MP, Barrell GK, Russell KN, Deane AR, Wynyard JR, Palmer MJ, Pulickan A, Prendergast PM, Casy W, Gray SJ, Palmer DN. Mitchell NL, et al. Among authors: murray sj. Front Genet. 2023 Aug 8;14:1212228. doi: 10.3389/fgene.2023.1212228. eCollection 2023. Front Genet. 2023. PMID: 37614821 Free PMC article.

3

Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC.

O'Leary C, Forte G, Mitchell NL, Youshani AS, Dyer A, Wellby MP, Russell KN, Murray SJ, Jolinon N, Jones SA, Stacey K, Davis DM, Henckaerts E, Palmer DN, Kamaly-Asl I, Bigger BW. O'Leary C, et al. Among authors: murray sj. J Transl Med. 2023 Jul 5;21(1):437. doi: 10.1186/s12967-023-04208-1. J Transl Med. 2023. PMID: 37407981 Free PMC article.

4

The shiny new object: Deconstructing the patient-oriented paradigm in health sciences.

Turcotte PL, Holmes D, Murray SJ. Turcotte PL, et al. Among authors: murray sj. J Eval Clin Pract. 2023 Aug;29(5):700-708. doi: 10.1111/jep.13823. Epub 2023 Mar 7. J Eval Clin Pract. 2023. PMID: 36880981

5

Progressive MRI brain volume changes in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinosis.

Murray SJ, Almuqbel MM, Felton SA, Palmer NJ, Myall DJ, Shoorangiz R, Ella A, Keller M, Palmer DN, Melzer TR, Mitchell NL. Murray SJ, et al. Brain Commun. 2023 Jan 2;5(1):fcac339. doi: 10.1093/braincomms/fcac339. eCollection 2023. Brain Commun. 2023. PMID: 36632184 Free PMC article.

6

Intravitreal Injections in the Ovine Eye.

Murray SJ, Mitchell NL. Murray SJ, et al. J Vis Exp. 2022 Jul 5;(185). doi: 10.3791/63823. J Vis Exp. 2022. PMID: 35876543

7

Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease).

Barry LA, Kay GW, Mitchell NL, Murray SJ, Jay NP, Palmer DN. Barry LA, et al. Among authors: murray sj. PLoS One. 2022 Apr 11;17(4):e0261544. doi: 10.1371/journal.pone.0261544. eCollection 2022. PLoS One. 2022. PMID: 35404973 Free PMC article.

8

Natural history of retinal degeneration in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinoses.

Murray SJ, Mitchell NL. Murray SJ, et al. Sci Rep. 2022 Mar 7;12(1):3670. doi: 10.1038/s41598-022-07612-7. Sci Rep. 2022. PMID: 35256654 Free PMC article.

9

The Translational Benefits of Sheep as Large Animal Models of Human Neurological Disorders.

Murray SJ, Mitchell NL. Murray SJ, et al. Front Vet Sci. 2022 Feb 15;9:831838. doi: 10.3389/fvets.2022.831838. eCollection 2022. Front Vet Sci. 2022. PMID: 35242840 Free PMC article. Review.

10

Phase II Study of Neoadjuvant Nivolumab in Patients with Locally Advanced Clear Cell Renal Cell Carcinoma Undergoing Nephrectomy.

Carlo MI, Attalla K, Mazaheri Y, Gupta S, Yildirim O, Murray SJ, Coskey DT, Kotecha R, Lee CH, Feldman DR, Russo P, Patil S, Motzer RJ, Coleman JA, Durack JC, Chen YB, Akin O, Ari Hakimi A, Voss MH. Carlo MI, et al. Among authors: murray sj. Eur Urol. 2022 Jun;81(6):570-573. doi: 10.1016/j.eururo.2022.01.043. Epub 2022 Feb 17. Eur Urol. 2022. PMID: 35183395 Free PMC article. Clinical Trial.

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