Huang J - Search Results

1

Optimization of the benzamide fragment targeting the S₂' site leads to potent dipeptidyl peptidase-IV inhibitors.

Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q. Deng X, et al. Among authors: huang j. Bioorg Chem. 2020 Jan;94:103366. doi: 10.1016/j.bioorg.2019.103366. Epub 2019 Oct 15. Bioorg Chem. 2020. PMID: 31640932

2

Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.

Huang J, Deng X, Zhou S, Wang N, Qin Y, Meng L, Li G, Xiong Y, Fan Y, Guo L, Lan D, Xing J, Jiang W, Li Q. Huang J, et al. Bioorg Med Chem. 2019 Feb 15;27(4):644-654. doi: 10.1016/j.bmc.2019.01.001. Epub 2019 Jan 4. Bioorg Med Chem. 2019. PMID: 30642693

3

Corrigendum to "Optimization of the benzamide fragment targeting the S₂' site leads to potent dipeptidyl Peptidase-IV inhibitors" [Bioorg. Chem. 94 (2020) 103366].

Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q. Deng X, et al. Among authors: huang j. Bioorg Chem. 2020 Jul;100:103898. doi: 10.1016/j.bioorg.2020.103898. Epub 2020 May 20. Bioorg Chem. 2020. PMID: 32416556 No abstract available.

4

Design, synthesis, and bioevaluation of imidazo [1,2-a] pyrazine derivatives as tubulin polymerization inhibitors with potent anticancer activities.

Deng B, Sun Z, Wang Y, Mai R, Yang Z, Ren Y, Liu J, Huang J, Ma Z, Chen T, Zeng C, Chen J. Deng B, et al. Among authors: huang j. Bioorg Med Chem. 2022 Dec 15;76:117098. doi: 10.1016/j.bmc.2022.117098. Epub 2022 Nov 19. Bioorg Med Chem. 2022. PMID: 36455508

5

Efficient Synthesis and Bioevaluation of Novel Dual Tubulin/Histone Deacetylase 3 Inhibitors as Potential Anticancer Agents.

Peng X, Chen J, Li L, Sun Z, Liu J, Ren Y, Huang J, Chen J. Peng X, et al. Among authors: huang j. J Med Chem. 2021 Jun 24;64(12):8447-8473. doi: 10.1021/acs.jmedchem.1c00413. Epub 2021 Jun 7. J Med Chem. 2021. PMID: 34097389

6

Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation.

Gong X, Li S, Huang J, Tan S, Zhang Q, Tian Y, Li Q, Wang L, Tong HHY, Yao X, Chen C, Lee SM, Liu H. Gong X, et al. Among authors: huang j. Eur J Med Chem. 2024 Dec 5;279:116812. doi: 10.1016/j.ejmech.2024.116812. Epub 2024 Aug 30. Eur J Med Chem. 2024. PMID: 39241668

7

Discovery of Thieno[2,3-d]pyrimidine-based KRAS G12D inhibitors as potential anticancer agents via combinatorial virtual screening.

Li L, Liu J, Yang Z, Zhao H, Deng B, Ren Y, Mai R, Huang J, Chen J. Li L, et al. Among authors: huang j. Eur J Med Chem. 2022 Apr 5;233:114243. doi: 10.1016/j.ejmech.2022.114243. Epub 2022 Mar 3. Eur J Med Chem. 2022. PMID: 35276423

8

Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases.

Huang J, Ma Z, Peng X, Yang Z, Wu Y, Zhong G, Ouyang T, Chen Z, Liu Y, Wang Q, Chen J, Chen T, Zeng Z. Huang J, et al. J Med Chem. 2024 Feb 22;67(4):2438-2465. doi: 10.1021/acs.jmedchem.3c01414. Epub 2024 Feb 6. J Med Chem. 2024. PMID: 38321747

9

Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8.

Sun Z, Deng B, Yang Z, Mai R, Huang J, Ma Z, Chen T, Chen J. Sun Z, et al. Among authors: huang j. Eur J Med Chem. 2022 Sep 5;239:114544. doi: 10.1016/j.ejmech.2022.114544. Epub 2022 Jun 21. Eur J Med Chem. 2022. PMID: 35759908

10

Effect of oil modification on the multiscale structure and gelatinization properties of crosslinked starch and their relationship with the texture and microstructure of surimi/starch composite gels.

Zhao X, Wang X, Li X, Zeng L, Huang J, Huang Q, Zhang B. Zhao X, et al. Among authors: huang q, huang j. Food Chem. 2022 Oct 15;391:133236. doi: 10.1016/j.foodchem.2022.133236. Epub 2022 May 18. Food Chem. 2022. PMID: 35609462

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