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Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ. Hobbs GA, et al. Among authors: wennerberg k. Cancer Discov. 2020 Jan;10(1):104-123. doi: 10.1158/2159-8290.CD-19-1006. Epub 2019 Oct 24. Cancer Discov. 2020. PMID: 31649109 Free PMC article.
RhoG signals in parallel with Rac1 and Cdc42.
Wennerberg K, Ellerbroek SM, Liu RY, Karnoub AE, Burridge K, Der CJ. Wennerberg K, et al. J Biol Chem. 2002 Dec 6;277(49):47810-7. doi: 10.1074/jbc.M203816200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376551 Free article.
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP.
Wennerberg K, Forget MA, Ellerbroek SM, Arthur WT, Burridge K, Settleman J, Der CJ, Hansen SH. Wennerberg K, et al. Curr Biol. 2003 Jul 1;13(13):1106-15. doi: 10.1016/s0960-9822(03)00418-4. Curr Biol. 2003. PMID: 12842009 Free PMC article.
The Ras superfamily at a glance.
Wennerberg K, Rossman KL, Der CJ. Wennerberg K, et al. J Cell Sci. 2005 Mar 1;118(Pt 5):843-6. doi: 10.1242/jcs.01660. J Cell Sci. 2005. PMID: 15731001 Review. No abstract available.
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.
Hayes TK, Neel NF, Hu C, Gautam P, Chenard M, Long B, Aziz M, Kassner M, Bryant KL, Pierobon M, Marayati R, Kher S, George SD, Xu M, Wang-Gillam A, Samatar AA, Maitra A, Wennerberg K, Petricoin EF 3rd, Yin HH, Nelkin B, Cox AD, Yeh JJ, Der CJ. Hayes TK, et al. Among authors: wennerberg k. Cancer Cell. 2016 Jan 11;29(1):75-89. doi: 10.1016/j.ccell.2015.11.011. Epub 2015 Dec 24. Cancer Cell. 2016. PMID: 26725216 Free PMC article.
162 results