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Page 1
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing.
Lu Y, Zheng Y, Coyaud É, Zhang C, Selvabaskaran A, Yu Y, Xu Z, Weng X, Chen JS, Meng Y, Warner N, Cheng X, Liu Y, Yao B, Hu H, Xia Z, Muise AM, Klip A, Brumell JH, Girardin SE, Ying S, Fairn GD, Raught B, Sun Q, Neculai D. Lu Y, et al. Among authors: fairn gd. Science. 2019 Oct 25;366(6464):460-467. doi: 10.1126/science.aau6391. Epub 2019 Oct 24. Science. 2019. PMID: 31649195
An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread.
Tan JMJ, Mellouk N, Osborne SE, Ammendolia DA, Dyer DN, Li R, Brunen D, van Rijn JM, Huang J, Czuczman MA, Cemma MA, Won AM, Yip CM, Xavier RJ, MacDuff DA, Reggiori F, Debnath J, Yoshimori T, Kim PK, Fairn GD, Coyaud E, Raught B, Muise AM, Higgins DE, Brumell JH. Tan JMJ, et al. Among authors: fairn gd. Nat Microbiol. 2018 Dec;3(12):1472-1485. doi: 10.1038/s41564-018-0293-5. Epub 2018 Nov 26. Nat Microbiol. 2018. PMID: 30478389
CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery.
Raheel H, Ghaffari S, Khosraviani N, Mintsopoulos V, Auyeung D, Wang C, Kim YH, Mullen B, Sung HK, Ho M, Fairn G, Neculai D, Febbraio M, Heit B, Lee WL. Raheel H, et al. Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L740-L750. doi: 10.1152/ajplung.00127.2018. Epub 2019 Jan 31. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30702342 Free PMC article.
Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase.
Walpole GFW, Pacheco J, Chauhan N, Clark J, Anderson KE, Abbas YM, Brabant-Kirwan D, Montaño-Rendón F, Liu Z, Zhu H, Brumell JH, Deiters A, Stephens LR, Hawkins PT, Hammond GRV, Grinstein S, Fairn GD. Walpole GFW, et al. Among authors: fairn gd. Nat Cell Biol. 2022 May;24(5):708-722. doi: 10.1038/s41556-022-00895-y. Epub 2022 Apr 28. Nat Cell Biol. 2022. PMID: 35484249 Free PMC article.
FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses.
Mekhail K, Lee M, Sugiyama M, Astori A, St-Germain J, Latreille E, Khosraviani N, Wei K, Li Z, Rini J, Lee WL, Antonescu C, Raught B, Fairn GD. Mekhail K, et al. Among authors: fairn gd. J Lipid Res. 2022 Sep;63(9):100256. doi: 10.1016/j.jlr.2022.100256. Epub 2022 Jul 31. J Lipid Res. 2022. PMID: 35921881 Free PMC article.
85 results