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RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism.
Liu W, Chen B, Wang Y, Meng C, Huang H, Huang XR, Qin J, Mulay SR, Anders HJ, Qiu A, Yang B, Freeman GJ, Lu HJ, Lin HY, Zheng ZH, Lan HY, Huang Y, Xia Y. Liu W, et al. Among authors: huang xr, huang h, huang y. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1475-E1484. doi: 10.1073/pnas.1716959115. Epub 2018 Jan 30. Proc Natl Acad Sci U S A. 2018. PMID: 29382757 Free PMC article.
Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage-p53-apoptosis pathway in renal tubular cells.
Huang H, Xu C, Wang Y, Meng C, Liu W, Zhao Y, Huang XR, You W, Feng B, Zheng ZH, Huang Y, Lan HY, Qin J, Xia Y. Huang H, et al. Among authors: huang xr, huang y. Kidney Int. 2018 Apr;93(4):855-870. doi: 10.1016/j.kint.2017.09.030. Epub 2017 Dec 21. Kidney Int. 2018. PMID: 29276099 Free article.
Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo.
Zhang Y, Wang Y, Zheng G, Liu Y, Li J, Huang H, Xu C, Zeng Y, Zhang X, Qin J, Dai C, Hambrock HO, Hartmann U, Feng B, Mak KK, Liu Y, Lan HY, Huang Y, Zheng ZH, Xia Y. Zhang Y, et al. Among authors: huang h, huang y. J Biol Chem. 2022 Jul;298(7):102010. doi: 10.1016/j.jbc.2022.102010. Epub 2022 May 4. J Biol Chem. 2022. PMID: 35525270 Free PMC article.
L3MBTL2 regulates chromatin remodeling during spermatogenesis.
Meng C, Liao J, Zhao D, Huang H, Qin J, Lee TL, Chen D, Chan WY, Xia Y. Meng C, et al. Among authors: huang h. Cell Death Differ. 2019 Nov;26(11):2194-2207. doi: 10.1038/s41418-019-0283-z. Epub 2019 Feb 13. Cell Death Differ. 2019. PMID: 30760872 Free PMC article.
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