Wu RH - Search Results

1

A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses.

Yang CC, Hu HS, Lin HM, Wu PS, Wu RH, Tian JN, Wu SH, Tsou LK, Song JS, Chen HW, Chern JH, Chen CT, Yueh A. Yang CC, et al. Among authors: wu sh, wu ps, wu rh. Antiviral Res. 2019 Dec;172:104636. doi: 10.1016/j.antiviral.2019.104636. Epub 2019 Oct 23. Antiviral Res. 2019. PMID: 31654671

2

Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus.

Yang CC, Tsai MH, Hu HS, Pu SY, Wu RH, Wu SH, Lin HM, Song JS, Chao YS, Yueh A. Yang CC, et al. Among authors: wu sh, wu rh. Antiviral Res. 2013 May;98(2):228-41. doi: 10.1016/j.antiviral.2013.03.001. Epub 2013 Mar 13. Antiviral Res. 2013. PMID: 23499649

3

A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease.

Yang CC, Hu HS, Wu RH, Wu SH, Lee SJ, Jiaang WT, Chern JH, Huang ZS, Wu HN, Chang CM, Yueh A. Yang CC, et al. Among authors: wu sh, wu rh, wu hn. Antimicrob Agents Chemother. 2014;58(1):110-9. doi: 10.1128/AAC.01281-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145533 Free PMC article.

4

A novel approach to propagate flavivirus infectious cDNA clones in bacteria by introducing tandem repeat sequences upstream of virus genome.

Pu SY, Wu RH, Tsai MH, Yang CC, Chang CM, Yueh A. Pu SY, et al. Among authors: wu rh. J Gen Virol. 2014 Jul;95(Pt 7):1493-1503. doi: 10.1099/vir.0.064915-0. Epub 2014 Apr 11. J Gen Virol. 2014. PMID: 24728712

5

Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A.

Tian JN, Wu RH, Chen SL, Chen CT, Yueh A. Tian JN, et al. Among authors: wu rh. J Gen Virol. 2019 Mar;100(3):457-470. doi: 10.1099/jgv.0.001227. Epub 2019 Feb 1. J Gen Virol. 2019. PMID: 30707666

6

Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes.

Pu SY, Wu RH, Yang CC, Jao TM, Tsai MH, Wang JC, Lin HM, Chao YS, Yueh A. Pu SY, et al. Among authors: wu rh. J Virol. 2011 Mar;85(6):2927-41. doi: 10.1128/JVI.01986-10. Epub 2011 Jan 12. J Virol. 2011. PMID: 21228244 Free PMC article.

7

Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-terminal half of dengue virus NS2A involved in viral RNA replication and virus assembly and secretion.

Wu RH, Tsai MH, Chao DY, Yueh A. Wu RH, et al. J Virol. 2015 Apr;89(8):4281-95. doi: 10.1128/JVI.03011-14. Epub 2015 Feb 4. J Virol. 2015. PMID: 25653435 Free PMC article.

8

Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments.

Wu RH, Tsai MH, Tsai KN, Tian JN, Wu JS, Wu SY, Chern JH, Chen CH, Yueh A. Wu RH, et al. Among authors: wu js, wu sy. J Virol. 2017 May 26;91(12):e01836-16. doi: 10.1128/JVI.01836-16. Print 2017 Jun 15. J Virol. 2017. PMID: 28381578 Free PMC article.

9

Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication.

Lin HM, Wu PS, Hu HS, Chang WC, Wu RH, Tian JN, Chern JH, Yueh A. Lin HM, et al. Among authors: wu ps, wu rh. J Virol Methods. 2018 Sep;259:10-17. doi: 10.1016/j.jviromet.2018.05.010. Epub 2018 May 18. J Virol Methods. 2018. PMID: 29782889

10

A Dengue Virus Type 2 (DENV-2) NS4B-Interacting Host Factor, SERP1, Reduces DENV-2 Production by Suppressing Viral RNA Replication.

Tian JN, Yang CC, Chuang CK, Tsai MH, Wu RH, Chen CT, Yueh A. Tian JN, et al. Among authors: wu rh. Viruses. 2019 Aug 27;11(9):787. doi: 10.3390/v11090787. Viruses. 2019. PMID: 31461934 Free PMC article.

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