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Page 1
Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide.
Nitta RT, Bolin S, Luo E, Solow-Codero DE, Samghabadi P, Purzner T, Aujla PS, Nwagbo G, Cho YJ, Li G. Nitta RT, et al. Among authors: purzner t. Oncogene. 2019 Oct;38(42):6867-6879. doi: 10.1038/s41388-019-0927-y. Epub 2019 Aug 12. Oncogene. 2019. PMID: 31406250 Free PMC article.
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.
Purzner T, Purzner J, Buckstaff T, Cozza G, Gholamin S, Rusert JM, Hartl TA, Sanders J, Conley N, Ge X, Langan M, Ramaswamy V, Ellis L, Litzenburger U, Bolin S, Theruvath J, Nitta R, Qi L, Li XN, Li G, Taylor MD, Wechsler-Reya RJ, Pinna LA, Cho YJ, Fuller MT, Elias JE, Scott MP. Purzner T, et al. Sci Signal. 2018 Sep 11;11(547):eaau5147. doi: 10.1126/scisignal.aau5147. Sci Signal. 2018. PMID: 30206138 Free PMC article.
LC-MS/MS method for quantitation of the CK2 inhibitor silmitasertib (CX-4945) in human plasma, CSF, and brain tissue, and application to a clinical pharmacokinetic study in children with brain tumors.
Zhong B, Campagne O, Salloum R, Purzner T, Stewart CF. Zhong B, et al. Among authors: purzner t. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Sep 1;1152:122254. doi: 10.1016/j.jchromb.2020.122254. Epub 2020 Jun 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 32615532 Free PMC article. Clinical Trial.
Adult isocitrate dehydrogenase-mutant brainstem glioma: illustrative case.
Ye VC, Landry AP, Purzner T, Kalyvas A, Mohan N, O'Halloran PJ, Gao A, Zadeh G. Ye VC, et al. Among authors: purzner t. J Neurosurg Case Lessons. 2021 Mar 22;1(12):CASE2078. doi: 10.3171/CASE2078. eCollection 2021 Mar 22. J Neurosurg Case Lessons. 2021. PMID: 35854925 Free PMC article.