Ryu S - Search Results

1

Dasotraline as a selective cytochrome 2B6 inhibitor for reaction phenotyping.

Yang X, Ryu S, Di L. Yang X, et al. Among authors: ryu s. Biopharm Drug Dispos. 2019 Nov;40(9):358-361. doi: 10.1002/bdd.2207. Biopharm Drug Dispos. 2019. PMID: 31674039

2

Human Tissue Distribution of Carbonyl Reductase 1 Using Proteomic Approach With Liquid Chromatography-Tandem Mass Spectrometry.

Hua W, Zhang H, Ryu S, Yang X, Di L. Hua W, et al. Among authors: ryu s. J Pharm Sci. 2017 May;106(5):1405-1411. doi: 10.1016/j.xphs.2017.01.024. Epub 2017 Feb 1. J Pharm Sci. 2017. PMID: 28161444

3

Novel Method to Predict In Vivo Liver-to-Plasma K_puu for OATP Substrates Using Suspension Hepatocytes.

Riccardi K, Lin J, Li Z, Niosi M, Ryu S, Hua W, Atkinson K, Kosa RE, Litchfield J, Di L. Riccardi K, et al. Among authors: ryu s. Drug Metab Dispos. 2017 May;45(5):576-580. doi: 10.1124/dmd.116.074575. Epub 2017 Mar 3. Drug Metab Dispos. 2017. PMID: 28258068

4

A Study on Pharmacokinetics of Bosentan with Systems Modeling, Part 1: Translating Systemic Plasma Concentration to Liver Exposure in Healthy Subjects.

Li R, Niosi M, Johnson N, Tess DA, Kimoto E, Lin J, Yang X, Riccardi KA, Ryu S, El-Kattan AF, Maurer TS, Tremaine LM, Di L. Li R, et al. Among authors: ryu s. Drug Metab Dispos. 2018 Apr;46(4):346-356. doi: 10.1124/dmd.117.078790. Epub 2018 Jan 12. Drug Metab Dispos. 2018. PMID: 29330218

5

Comparison of Species and Cell-Type Differences in Fraction Unbound of Liver Tissues, Hepatocytes, and Cell Lines.

Riccardi K, Ryu S, Lin J, Yates P, Tess D, Li R, Singh D, Holder BR, Kapinos B, Chang G, Di L. Riccardi K, et al. Among authors: ryu s. Drug Metab Dispos. 2018 Apr;46(4):415-421. doi: 10.1124/dmd.117.079152. Epub 2018 Feb 2. Drug Metab Dispos. 2018. PMID: 29437874

6

11β-Hydroxysteroid Dehydrogenase 1 Human Tissue Distribution, Selective Inhibitor, and Role in Doxorubicin Metabolism.

Yang X, Hua W, Ryu S, Yates P, Chang C, Zhang H, Di L. Yang X, et al. Among authors: ryu s. Drug Metab Dispos. 2018 Jul;46(7):1023-1029. doi: 10.1124/dmd.118.081083. Epub 2018 Apr 19. Drug Metab Dispos. 2018. PMID: 29674492

7

6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to β-Estradiol.

Lapham K, Lin J, Novak J, Orozco C, Niosi M, Di L, Goosen TC, Ryu S, Riccardi K, Eng H, Cameron KO, Kalgutkar AS. Lapham K, et al. Among authors: ryu s. Drug Metab Dispos. 2018 Dec;46(12):1836-1846. doi: 10.1124/dmd.118.083709. Epub 2018 Sep 7. Drug Metab Dispos. 2018. PMID: 30194276

8

The impact of low temperature on fraction unbound for plasma and tissue.

Ryu S, Novak JJ, Patel R, Yates P, Di L. Ryu S, et al. Biopharm Drug Dispos. 2018 Nov;39(9):437-442. doi: 10.1002/bdd.2160. Epub 2018 Nov 13. Biopharm Drug Dispos. 2018. PMID: 30362129

9

A Novel Unified Approach to Predict Human Hepatic Clearance for Both Enzyme- and Transporter-Mediated Mechanisms Using Suspended Human Hepatocytes.

Riccardi KA, Tess DA, Lin J, Patel R, Ryu S, Atkinson K, Di L, Li R. Riccardi KA, et al. Among authors: ryu s. Drug Metab Dispos. 2019 May;47(5):484-492. doi: 10.1124/dmd.118.085639. Epub 2019 Feb 20. Drug Metab Dispos. 2019. PMID: 30787098

10

Applying Two Orthogonal Methods to Assess Accuracy of Plasma Protein Binding Measurements for Highly Bound Compounds.

Ryu S, Riccardi K, Patel R, Zueva L, Burchett W, Di L. Ryu S, et al. J Pharm Sci. 2019 Nov;108(11):3745-3749. doi: 10.1016/j.xphs.2019.08.004. Epub 2019 Aug 13. J Pharm Sci. 2019. PMID: 31419399

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