Tan W - Search Results

1

Pivotal Considerations for Optimal Deployment of Healthy Volunteers in Oncology Drug Development.

Ahmed MA, Patel C, Drezner N, Helms W, Tan W, Stypinski D. Ahmed MA, et al. Among authors: tan w. Clin Transl Sci. 2020 Jan;13(1):31-40. doi: 10.1111/cts.12703. Epub 2019 Oct 31. Clin Transl Sci. 2020. PMID: 31674150 Free PMC article. Review.

2

Impact of posaconazole and diltiazem on pharmacokinetics of encorafenib, a BRAF V600 kinase inhibitor for melanoma and colorectal cancer with BRAF mutations.

Hahn E, Chavira R, Wollenberg L, Tan W, Reddy MB. Hahn E, et al. Among authors: tan w. Clin Transl Sci. 2023 Dec;16(12):2675-2686. doi: 10.1111/cts.13662. Epub 2023 Nov 4. Clin Transl Sci. 2023. PMID: 37837178 Free PMC article.

3

Evaluation of crizotinib absolute bioavailability, the bioequivalence of three oral formulations, and the effect of food on crizotinib pharmacokinetics in healthy subjects.

Xu H, O'Gorman M, Boutros T, Brega N, Kantaridis C, Tan W, Bello A. Xu H, et al. Among authors: tan w. J Clin Pharmacol. 2015 Jan;55(1):104-13. doi: 10.1002/jcph.356. Epub 2014 Jul 11. J Clin Pharmacol. 2015. PMID: 24990113 Clinical Trial.

4

Clinical implications of an analysis of pharmacokinetics of crizotinib coadministered with dexamethasone in patients with non-small cell lung cancer.

Lin S, Nickens DJ, Patel M, Wilner KD, Tan W. Lin S, et al. Among authors: tan w. Cancer Chemother Pharmacol. 2019 Jul;84(1):203-211. doi: 10.1007/s00280-019-03861-y. Epub 2019 May 24. Cancer Chemother Pharmacol. 2019. PMID: 31127319

5

Evaluation of Proton Pump Inhibitor Esomeprazole on Crizotinib Pharmacokinetics in Healthy Participants.

Xu H, O'Gorman M, Matschke K, Boutros T, Brega N, Tan W, Bello A. Xu H, et al. Among authors: tan w. Clin Pharmacol Drug Dev. 2022 Jan;11(1):34-42. doi: 10.1002/cpdd.1032. Epub 2021 Nov 26. Clin Pharmacol Drug Dev. 2022. PMID: 34825782 Free PMC article. Clinical Trial.

6

Effects of Renal Function on Crizotinib Pharmacokinetics: Dose Recommendations for Patients with ALK-Positive Non-Small Cell Lung Cancer.

Tan W, Yamazaki S, Johnson TR, Wang R, O'Gorman MT, Kirkovsky L, Boutros T, Brega NM, Bello A. Tan W, et al. Clin Drug Investig. 2017 Apr;37(4):363-373. doi: 10.1007/s40261-016-0490-z. Clin Drug Investig. 2017. PMID: 28035616

7

Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer.

Poels KE, Schoenfeld AJ, Makhnin A, Tobi Y, Wang Y, Frisco-Cabanos H, Chakrabarti S, Shi M, Napoli C, McDonald TO, Tan W, Hata A, Weinrich SL, Yu HA, Michor F. Poels KE, et al. Among authors: tan w. Nat Commun. 2021 Jun 17;12(1):3697. doi: 10.1038/s41467-021-23912-4. Nat Commun. 2021. PMID: 34140482 Free PMC article. Clinical Trial.

8

Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects.

Johnson TR, Tan W, Goulet L, Smith EB, Yamazaki S, Walker GS, O'Gorman MT, Bedarida G, Zou HY, Christensen JG, Nguyen LN, Shen Z, Dalvie D, Bello A, Smith BJ. Johnson TR, et al. Among authors: tan w. Xenobiotica. 2015 Jan;45(1):45-59. doi: 10.3109/00498254.2014.941964. Epub 2014 Jul 18. Xenobiotica. 2015. PMID: 25034009

9

The Effect of Hepatic Impairment on the Pharmacokinetics of Dacomitinib.

Piscitelli J, Chen J, LaBadie RR, Salageanu J, Chung CH, Tan W. Piscitelli J, et al. Among authors: tan w. Clin Drug Investig. 2022 Mar;42(3):221-235. doi: 10.1007/s40261-022-01125-x. Epub 2022 Feb 23. Clin Drug Investig. 2022. PMID: 35195881 Free PMC article. Clinical Trial.

10

Effects of H2-Receptor Antagonists on the Exposure of Dacomitinib.

Liu J, Lin S, Huynh A, Tan W. Liu J, et al. Among authors: tan w. Pharmaceutics. 2024 Jan 17;16(1):118. doi: 10.3390/pharmaceutics16010118. Pharmaceutics. 2024. PMID: 38258127 Free PMC article.

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