Bassik MC - Search Results

1

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins.

Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, Yao D, Altman RB, Sello JK, Denic V, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Elife. 2019 Nov 1;8:e48434. doi: 10.7554/eLife.48434. Elife. 2019. PMID: 31674906 Free PMC article.

2

Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.

Latallo MJ, Wang S, Dong D, Nelson B, Livingston NM, Wu R, Zhao N, Stasevich TJ, Bassik MC, Sun S, Wu B. Latallo MJ, et al. Among authors: bassik mc. Nat Commun. 2023 Sep 11;14(1):5581. doi: 10.1038/s41467-023-41339-x. Nat Commun. 2023. PMID: 37696852 Free PMC article.

3

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.

Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Deans RM, et al. Among authors: bassik mc. Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018887 Free PMC article.

4

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.

Morgens DW, Deans RM, Li A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Biotechnol. 2016 Jun;34(6):634-6. doi: 10.1038/nbt.3567. Epub 2016 May 9. Nat Biotechnol. 2016. PMID: 27159373 Free PMC article.

5

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.

Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Hess GT, et al. Among authors: bassik mc. Nat Methods. 2016 Dec;13(12):1036-1042. doi: 10.1038/nmeth.4038. Epub 2016 Oct 31. Nat Methods. 2016. PMID: 27798611 Free PMC article.

6

Finding host targets for HIV therapy.

Tsui CK, Gupta A, Bassik MC. Tsui CK, et al. Among authors: bassik mc. Nat Genet. 2017 Jan 31;49(2):175-176. doi: 10.1038/ng.3777. Nat Genet. 2017. PMID: 28138150

7

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Han K, et al. Among authors: bassik mc. Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20. Nat Biotechnol. 2017. PMID: 28319085 Free PMC article.

8

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.

Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178. Nat Commun. 2017. PMID: 28474669 Free PMC article.

9

Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development.

Phanstiel DH, Van Bortle K, Spacek D, Hess GT, Shamim MS, Machol I, Love MI, Aiden EL, Bassik MC, Snyder MP. Phanstiel DH, et al. Among authors: bassik mc. Mol Cell. 2017 Sep 21;67(6):1037-1048.e6. doi: 10.1016/j.molcel.2017.08.006. Epub 2017 Sep 7. Mol Cell. 2017. PMID: 28890333 Free PMC article.

10

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.

Hess GT, Tycko J, Yao D, Bassik MC. Hess GT, et al. Among authors: bassik mc. Mol Cell. 2017 Oct 5;68(1):26-43. doi: 10.1016/j.molcel.2017.09.029. Mol Cell. 2017. PMID: 28985508 Free PMC article. Review.

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