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KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, Izzo M, Infante P, Miele E, Po A, Di Magno L, Magliozzi R, Guardavaccaro D, Maroder M, Canettieri G, Giannini G, Ferretti E, Gulino A, Di Marcotullio L, Moretti M, De Smaele E. Spiombi E, et al. Among authors: di marcotullio l, di magno l. Oncogenesis. 2019 Nov 4;8(11):64. doi: 10.1038/s41389-019-0175-6. Oncogenesis. 2019. PMID: 31685809 Free PMC article.
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Canettieri G, Coni S, Della Guardia M, Nocerino V, Antonucci L, Di Magno L, Screaton R, Screpanti I, Giannini G, Gulino A. Canettieri G, et al. Among authors: di magno l. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1445-50. doi: 10.1073/pnas.0808749106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164581 Free PMC article.
TORCs/CRTCs: more than mere coincidence.
Canettieri G, Coni S, Antonucci L, Di Magno L, Gulino A. Canettieri G, et al. Among authors: di magno l. Cell Cycle. 2009 Apr 1;8(7):963-4. Epub 2009 Apr 9. Cell Cycle. 2009. PMID: 19287208 No abstract available.
Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth.
D'Amico D, Antonucci L, Di Magno L, Coni S, Sdruscia G, Macone A, Miele E, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Ciapponi L, Giangaspero F, Yates JR 3rd, Agostinelli E, Cardinali B, Screpanti I, Gulino A, Canettieri G. D'Amico D, et al. Among authors: di marcotullio l, di magno l. Dev Cell. 2015 Oct 12;35(1):21-35. doi: 10.1016/j.devcel.2015.09.008. Dev Cell. 2015. PMID: 26460945 Free PMC article.
37 results