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In vitro fertilization does not increase the incidence of de novo copy number alterations in fetal and placental lineages.
Zamani Esteki M, Viltrop T, Tšuiko O, Tiirats A, Koel M, Nõukas M, Žilina O, Teearu K, Marjonen H, Kahila H, Meekels J, Söderström-Anttila V, Suikkari AM, Tiitinen A, Mägi R, Kõks S, Kaminen-Ahola N, Kurg A, Voet T, Vermeesch JR, Salumets A. Zamani Esteki M, et al. Among authors: tiirats a. Nat Med. 2019 Nov;25(11):1699-1705. doi: 10.1038/s41591-019-0620-2. Epub 2019 Nov 4. Nat Med. 2019. PMID: 31686035
rs10732516 polymorphism at the IGF2/H19 locus associates with genotype-specific effects on placental DNA methylation and birth weight of newborns conceived by assisted reproductive technology.
Marjonen H, Auvinen P, Kahila H, Tšuiko O, Kõks S, Tiirats A, Viltrop T, Tuuri T, Söderström-Anttila V, Suikkari AM, Salumets A, Tiitinen A, Kaminen-Ahola N. Marjonen H, et al. Among authors: tiirats a. Clin Epigenetics. 2018 Jun 18;10:80. doi: 10.1186/s13148-018-0511-2. eCollection 2018. Clin Epigenetics. 2018. PMID: 29946374 Free PMC article.