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Transcriptional dysregulation by a nucleus-localized aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth neuropathy.
Bervoets S, Wei N, Erfurth ML, Yusein-Myashkova S, Ermanoska B, Mateiu L, Asselbergh B, Blocquel D, Kakad P, Penserga T, Thomas FP, Guergueltcheva V, Tournev I, Godenschwege T, Jordanova A, Yang XL. Bervoets S, et al. Among authors: yang xl. Nat Commun. 2019 Nov 6;10(1):5045. doi: 10.1038/s41467-019-12909-9. Nat Commun. 2019. PMID: 31695036 Free PMC article.
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy.
Storkebaum E, Leitão-Gonçalves R, Godenschwege T, Nangle L, Mejia M, Bosmans I, Ooms T, Jacobs A, Van Dijck P, Yang XL, Schimmel P, Norga K, Timmerman V, Callaerts P, Jordanova A. Storkebaum E, et al. Among authors: yang xl. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11782-7. doi: 10.1073/pnas.0905339106. Epub 2009 Jun 26. Proc Natl Acad Sci U S A. 2009. PMID: 19561293 Free PMC article.
Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality.
Zhou Q, Kapoor M, Guo M, Belani R, Xu X, Kiosses WB, Hanan M, Park C, Armour E, Do MH, Nangle LA, Schimmel P, Yang XL. Zhou Q, et al. Among authors: yang xl. Nat Struct Mol Biol. 2010 Jan;17(1):57-61. doi: 10.1038/nsmb.1706. Epub 2009 Dec 13. Nat Struct Mol Biol. 2010. PMID: 20010843 Free PMC article.
New functions of aminoacyl-tRNA synthetases beyond translation.
Guo M, Yang XL, Schimmel P. Guo M, et al. Among authors: yang xl. Nat Rev Mol Cell Biol. 2010 Sep;11(9):668-74. doi: 10.1038/nrm2956. Epub 2010 Aug 11. Nat Rev Mol Cell Biol. 2010. PMID: 20700144 Free PMC article. Review.
1,638 results