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Page 1
Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse.
Neganova I, Al-Qassab H, Heffron H, Selman C, Choudhury AI, Lingard SJ, Diakonov I, Patterson M, Ghatei M, Bloom SR, Franks S, Huhtaniemi I, Hardy K, Withers DJ. Neganova I, et al. Among authors: withers dj. Biol Reprod. 2007 Jun;76(6):1045-53. doi: 10.1095/biolreprod.106.059360. Epub 2007 Feb 28. Biol Reprod. 2007. PMID: 17329594
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, Thornton JM, Gems D, Partridge L, Withers DJ. Selman C, et al. Among authors: withers dj. FASEB J. 2008 Mar;22(3):807-18. doi: 10.1096/fj.07-9261com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17928362
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice.
Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, Lovestone S. Killick R, et al. Among authors: withers dj. Biochem Biophys Res Commun. 2009 Aug 14;386(1):257-62. doi: 10.1016/j.bbrc.2009.06.032. Epub 2009 Jun 10. Biochem Biophys Res Commun. 2009. PMID: 19523444 Free PMC article.
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, Thomas G, Carling D, Okkenhaug K, Thornton JM, Partridge L, Gems D, Withers DJ. Selman C, et al. Among authors: withers dj. Science. 2009 Oct 2;326(5949):140-4. doi: 10.1126/science.1177221. Science. 2009. PMID: 19797661 Free PMC article.
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, Selman C, Piipari K, Clements M, Lingard S, Chandarana K, Bell JD, Barsh GS, Smith AJ, Batterham RL, Ashford ML, Vanhaesebroeck B, Withers DJ. Al-Qassab H, et al. Among authors: withers dj. Cell Metab. 2009 Nov;10(5):343-54. doi: 10.1016/j.cmet.2009.09.008. Cell Metab. 2009. PMID: 19883613 Free PMC article.
Insulin receptor substrate 2 is a negative regulator of memory formation.
Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP. Irvine EE, et al. Among authors: withers dj. Learn Mem. 2011 May 19;18(6):375-83. doi: 10.1101/lm.2111311. Print 2011 Jun. Learn Mem. 2011. PMID: 21597043 Free PMC article.
119 results