Rennie P - Search Results

1

Androgen receptor plasticity and its implications for prostate cancer therapy.

Snow O, Lallous N, Singh K, Lack N, Rennie P, Cherkasov A. Snow O, et al. Among authors: rennie p. Cancer Treat Rev. 2019 Dec;81:101871. doi: 10.1016/j.ctrv.2019.05.001. Epub 2019 Jun 11. Cancer Treat Rev. 2019. PMID: 31698174 Review.

2

Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.

Axerio-Cilies P, Lack NA, Nayana MR, Chan KH, Yeung A, Leblanc E, Guns ES, Rennie PS, Cherkasov A. Axerio-Cilies P, et al. Among authors: rennie ps. J Med Chem. 2011 Sep 22;54(18):6197-205. doi: 10.1021/jm200532b. Epub 2011 Aug 29. J Med Chem. 2011. PMID: 21846139

3

Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.

Lack NA, Axerio-Cilies P, Tavassoli P, Han FQ, Chan KH, Feau C, LeBlanc E, Guns ET, Guy RK, Rennie PS, Cherkasov A. Lack NA, et al. Among authors: rennie ps. J Med Chem. 2011 Dec 22;54(24):8563-73. doi: 10.1021/jm201098n. Epub 2011 Nov 18. J Med Chem. 2011. PMID: 22047606 Free PMC article.

4

Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.

Lallous N, Dalal K, Cherkasov A, Rennie PS. Lallous N, et al. Int J Mol Sci. 2013 Jun 14;14(6):12496-519. doi: 10.3390/ijms140612496. Int J Mol Sci. 2013. PMID: 23771019 Free PMC article. Review.

5

Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer.

Li H, Hassona MD, Lack NA, Axerio-Cilies P, Leblanc E, Tavassoli P, Kanaan N, Frewin K, Singh K, Adomat H, Böhm KJ, Prinz H, Guns ET, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. Mol Cancer Ther. 2013 Nov;12(11):2425-35. doi: 10.1158/1535-7163.MCT-13-0267. Epub 2013 Aug 12. Mol Cancer Ther. 2013. PMID: 23939374

6

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hessein M, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Dalal K, et al. J Biol Chem. 2014 Sep 19;289(38):26417-26429. doi: 10.1074/jbc.M114.553818. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086042 Free PMC article.

7

Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients.

Lallous N, Volik SV, Awrey S, Leblanc E, Tse R, Murillo J, Singh K, Azad AA, Wyatt AW, LeBihan S, Chi KN, Gleave ME, Rennie PS, Collins CC, Cherkasov A. Lallous N, et al. Genome Biol. 2016 Jan 26;17:10. doi: 10.1186/s13059-015-0864-1. Genome Biol. 2016. PMID: 26813233 Free PMC article.

8

Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor.

Dalal K, Munuganti R, Morin H, Lallous N, Rennie PS, Cherkasov A. Dalal K, et al. Methods Mol Biol. 2016;1443:31-54. doi: 10.1007/978-1-4939-3724-0_4. Methods Mol Biol. 2016. PMID: 27246333

9

Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation.

Lallous N, Leblanc E, Munuganti RS, Hassona MD, Nakouzi NA, Awrey S, Morin H, Roshan-Moniri M, Singh K, Lawn S, Yamazaki T, Adomat HH, Andre C, Daugaard M, Young RN, Guns ES, Rennie PS, Cherkasov A. Lallous N, et al. Mol Cancer Ther. 2016 Dec;15(12):2936-2945. doi: 10.1158/1535-7163.MCT-16-0354. Epub 2016 Oct 7. Mol Cancer Ther. 2016. PMID: 27765852 Free PMC article.

10

Cheminformatics Modeling of Adverse Drug Responses by Clinically Relevant Mutants of Human Androgen Receptor.

Paul N, Carabet LA, Lallous N, Yamazaki T, Gleave ME, Rennie PS, Cherkasov A. Paul N, et al. J Chem Inf Model. 2016 Dec 27;56(12):2507-2516. doi: 10.1021/acs.jcim.6b00400. Epub 2016 Nov 18. J Chem Inf Model. 2016. PMID: 28024400

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