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Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.
Blood Adv. 2019 Nov 12;3(21):3379-3392. doi: 10.1182/bloodadvances.2019000820.
Blood Adv. 2019.
PMID: 31698466
Free PMC article.
Base editing of haematopoietic stem cells rescues sickle cell disease in mice.
Newby GA, Yen JS, Woodard KJ, Mayuranathan T, Lazzarotto CR, Li Y, Sheppard-Tillman H, Porter SN, Yao Y, Mayberry K, Everette KA, Jang Y, Podracky CJ, Thaman E, Lechauve C, Sharma A, Henderson JM, Richter MF, Zhao KT, Miller SM, Wang T, Koblan LW, McCaffrey AP, Tisdale JF, Kalfa TA, Pruett-Miller SM, Tsai SQ, Weiss MJ, Liu DR.
Newby GA, et al. Among authors: woodard kj.
Nature. 2021 Jul;595(7866):295-302. doi: 10.1038/s41586-021-03609-w. Epub 2021 Jun 2.
Nature. 2021.
PMID: 34079130
Free PMC article.
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A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ.
Traxler EA, et al. Among authors: woodard kj.
Nat Med. 2016 Sep;22(9):987-90. doi: 10.1038/nm.4170. Epub 2016 Aug 15.
Nat Med. 2016.
PMID: 27525524
Free PMC article.
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Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations.
Woodard KJ, Doerfler PA, Mayberry KD, Sharma A, Levine R, Yen J, Valentine V, Palmer LE, Valentine M, Weiss MJ.
Woodard KJ, et al.
Dis Model Mech. 2022 Jun 1;15(6):dmm049463. doi: 10.1242/dmm.049463. Epub 2022 Jul 6.
Dis Model Mech. 2022.
PMID: 35793591
Free PMC article.
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