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A suicide inhibitor of nematode trehalose-6-phosphate phosphatases.
Cross M, York M, Długosz E, Straub JH, Biberacher S, Herath HMPD, Logan SA, Kim JS, Gasser RB, Ryan JH, Hofmann A. Cross M, et al. Sci Rep. 2019 Nov 7;9(1):16165. doi: 10.1038/s41598-019-52593-9. Sci Rep. 2019. PMID: 31700060 Free PMC article.
Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings.
Cross M, Lepage R, Rajan S, Biberacher S, Young ND, Kim BN, Coster MJ, Gasser RB, Kim JS, Hofmann A. Cross M, et al. FASEB J. 2017 Mar;31(3):920-926. doi: 10.1096/fj.201601149R. Epub 2016 Nov 18. FASEB J. 2017. PMID: 27864376
Therefore, we suggest that homology-based inference of functionally important amino acids by sequence comparison for monoenzyme TPPs should only be carried out for each of the 3 groups.-Cross, M., Lepage, R., Rajan, S., Biberacher, S., Young, N. D., Kim, B.-N., Cost …
Therefore, we suggest that homology-based inference of functionally important amino acids by sequence comparison for monoenzyme TPPs should …
Trehalose 6-phosphate phosphatases of Pseudomonas aeruginosa.
Cross M, Biberacher S, Park SY, Rajan S, Korhonen P, Gasser RB, Kim JS, Coster MJ, Hofmann A. Cross M, et al. FASEB J. 2018 Oct;32(10):5470-5482. doi: 10.1096/fj.201800500R. Epub 2018 Apr 24. FASEB J. 2018. PMID: 29688811
The 3-dimensional crystal structure of the chromosomal TPP revealed a protein dimer arising through beta-sheet expansion of the individual monomers, which possess the overall fold of halo-acid dehydrogenases.-Cross, M., Biberacher, S., Park, S.-Y., Rajan, S., Korhon …
The 3-dimensional crystal structure of the chromosomal TPP revealed a protein dimer arising through beta-sheet expansion of the individual m …
1,456 results