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Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulation by lipid IVa.
Scior T, Alexander C, Zaehringer U. Scior T, et al. Comput Struct Biotechnol J. 2013 Apr 5;5:e201302012. doi: 10.5936/csbj.201302012. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688705 Free PMC article. Review.
Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of Lipid IVA in the mammalian LPS sensor system.
Scior T, Lozano-Aponte J, Figueroa-Vazquez V, Yunes-Rojas JA, Zähringer U, Alexander C. Scior T, et al. Comput Struct Biotechnol J. 2013 Aug 8;7:e201305003. doi: 10.5936/csbj.201305003. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688739 Free PMC article.
54 results