Retrocyclins neutralize bacterial toxins by potentiating their unfolding.
Kudryashova E, Seveau S, Lu W, Kudryashov DS.
Kudryashova E, et al.
Biochem J. 2015 Apr 15;467(2):311-20. doi: 10.1042/BJ20150049.
Biochem J. 2015.
PMID: 25670244
Free PMC article.
Recently, we have demonstrated that in the case of human alpha- and beta-defensins, this later ability is achieved through exploiting toxins' marginal thermodynamic stability, i.e. defensins act as molecular anti-chaperones unfolding toxin molecules and exposing their hydr …
Recently, we have demonstrated that in the case of human alpha- and beta-defensins, this later ability is achieved through exploiting toxins …