Golani LK - Search Results

1

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

McCusker P, Mian MY, Li G, Olp MD, Tiruveedhula VVNPB, Rashid F, Golani LK, Verma RS, Smith BC, Cook JM, Chan JD. McCusker P, et al. Among authors: golani lk. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007826. doi: 10.1371/journal.pntd.0007826. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730614 Free PMC article.

2

An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABA_A receptors.

Methuku KR, Li X, Cerne R, Gleason SD, Schkeryantz JM, Tiruveedhula VVNPB, Golani LK, Li G, Poe MM, Rahman MT, Cook JM, Fisher JL, Witkin JM. Methuku KR, et al. Among authors: golani lk. Pharmacol Biochem Behav. 2018 Jul;170:9-13. doi: 10.1016/j.pbb.2018.04.009. Epub 2018 Apr 30. Pharmacol Biochem Behav. 2018. PMID: 29715490

3

Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam.

Moerke MJ, Li G, Golani LK, Cook J, Negus SS. Moerke MJ, et al. Among authors: golani lk. Behav Pharmacol. 2019 Aug;30(5):452-461. doi: 10.1097/FBP.0000000000000464. Behav Pharmacol. 2019. PMID: 30640180 Free PMC article.

4

The α2,3-selective potentiator of GABA_A receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats.

Witkin JM, Cerne R, Davis PG, Freeman KB, do Carmo JM, Rowlett JK, Methuku KR, Okun A, Gleason SD, Li X, Krambis MJ, Poe M, Li G, Schkeryantz JM, Jahan R, Yang L, Guo W, Golani LK, Anderson WH, Catlow JT, Jones TM, Porreca F, Smith JL, Knopp KL, Cook JM. Witkin JM, et al. Among authors: golani lk. Pharmacol Biochem Behav. 2019 May;180:22-31. doi: 10.1016/j.pbb.2019.02.013. Epub 2019 Feb 27. Pharmacol Biochem Behav. 2019. PMID: 30825491 Free PMC article.

5

GABA_A Receptor Subtypes and the Abuse-Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators.

Berro LF, Rüedi-Bettschen D, Cook JE, Golani LK, Li G, Jahan R, Rashid F, Cook JM, Rowlett JK, Platt DM. Berro LF, et al. Among authors: golani lk. Alcohol Clin Exp Res. 2019 May;43(5):791-802. doi: 10.1111/acer.14000. Epub 2019 Apr 8. Alcohol Clin Exp Res. 2019. PMID: 30861153 Free PMC article.

6

The Positive Allosteric Modulator of α2/3-Containing GABA_A Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury.

Witkin JM, Li G, Golani LK, Xiong W, Smith JL, Ping X, Rashid F, Jahan R, Cerne R, Cook JM, Jin X. Witkin JM, et al. Among authors: golani lk. J Pharmacol Exp Ther. 2020 Jan;372(1):83-94. doi: 10.1124/jpet.119.260968. Epub 2019 Nov 6. J Pharmacol Exp Ther. 2020. PMID: 31694876 Free PMC article.

7

The α2,3-selective potentiators of GABA_A receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without tolerance development.

Biggerstaff A, Kivell B, Smith JL, Mian MY, Golani LK, Rashid F, Sharmin D, Knutson DE, Cerne R, Cook JM, Witkin JM. Biggerstaff A, et al. Among authors: golani lk. Pharmacol Biochem Behav. 2020 Sep;196:172996. doi: 10.1016/j.pbb.2020.172996. Epub 2020 Jul 12. Pharmacol Biochem Behav. 2020. PMID: 32668266

8

Improved Synthesis of Anxiolytic, Anticonvulsant and Antinociceptive α2/α3-GABA(A)ergic Receptor Subtype Selective Ligands as Promising Agents to Treat Anxiety, Epilepsy, as well as Neuropathic Pain.

Li G, Golani LK, Jahan R, Rashid F, Cook JM. Li G, et al. Among authors: golani lk. Synthesis (Stuttg). 2018 Oct;50(20):4124-4132. doi: 10.1055/s-0037-1610211. Synthesis (Stuttg). 2018. PMID: 32773890 Free PMC article.

9

Imidazodiazepine Anticonvulsant, KRM-II-81, Produces Novel, Non-diazepam-like Antiseizure Effects.

Knutson DE, Smith JL, Ping X, Jin X, Golani LK, Li G, Tiruveedhula VVNPB, Rashid F, Mian MY, Jahan R, Sharmin D, Cerne R, Cook JM, Witkin JM. Knutson DE, et al. Among authors: golani lk. ACS Chem Neurosci. 2020 Sep 2;11(17):2624-2637. doi: 10.1021/acschemneuro.0c00295. Epub 2020 Aug 18. ACS Chem Neurosci. 2020. PMID: 32786313

10

Blockade of α1 subtype GABAA receptors attenuates the development of tolerance to the antinociceptive effects of midazolam in rats.

Lewter LA, Golani LK, Cook JM, Li JX. Lewter LA, et al. Among authors: golani lk. Behav Pharmacol. 2021 Jun 1;32(4):345-350. doi: 10.1097/FBP.0000000000000614. Behav Pharmacol. 2021. PMID: 33290344 Free PMC article.

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