Li G - Search Results

1

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

McCusker P, Mian MY, Li G, Olp MD, Tiruveedhula VVNPB, Rashid F, Golani LK, Verma RS, Smith BC, Cook JM, Chan JD. McCusker P, et al. Among authors: li g. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007826. doi: 10.1371/journal.pntd.0007826. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730614 Free PMC article.

2

Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABA_A Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.

Duke AN, Meng Z, Platt DM, Atack JR, Dawson GR, Reynolds DS, Tiruveedhula VVNPB, Li G, Stephen MR, Sieghart W, Cook JM, Rowlett JK. Duke AN, et al. Among authors: li g. J Pharmacol Exp Ther. 2018 Jul;366(1):145-157. doi: 10.1124/jpet.118.249250. Epub 2018 May 2. J Pharmacol Exp Ther. 2018. PMID: 29720564 Free PMC article.

3

Imidazodiazepine Anticonvulsant, KRM-II-81, Produces Novel, Non-diazepam-like Antiseizure Effects.

Knutson DE, Smith JL, Ping X, Jin X, Golani LK, Li G, Tiruveedhula VVNPB, Rashid F, Mian MY, Jahan R, Sharmin D, Cerne R, Cook JM, Witkin JM. Knutson DE, et al. Among authors: li g. ACS Chem Neurosci. 2020 Sep 2;11(17):2624-2637. doi: 10.1021/acschemneuro.0c00295. Epub 2020 Aug 18. ACS Chem Neurosci. 2020. PMID: 32786313

4

Attaining in vivo selectivity of positive modulation of α3βγ2 GABA_A receptors in rats: A hard task!

Batinić B, Stanković T, Stephen MR, Kodali R, Tiruveedhula VV, Li G, Scholze P, Marković BD, Obradović AL, Ernst M, Cook JM, Savić MM. Batinić B, et al. Among authors: li g. Eur Neuropsychopharmacol. 2018 Aug;28(8):903-914. doi: 10.1016/j.euroneuro.2018.05.014. Epub 2018 Jun 19. Eur Neuropsychopharmacol. 2018. PMID: 29891214

5

Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam.

Moerke MJ, Li G, Golani LK, Cook J, Negus SS. Moerke MJ, et al. Among authors: li g. Behav Pharmacol. 2019 Aug;30(5):452-461. doi: 10.1097/FBP.0000000000000464. Behav Pharmacol. 2019. PMID: 30640180 Free PMC article.

6

The Positive Allosteric Modulator of α2/3-Containing GABA_A Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury.

Witkin JM, Li G, Golani LK, Xiong W, Smith JL, Ping X, Rashid F, Jahan R, Cerne R, Cook JM, Jin X. Witkin JM, et al. Among authors: li g. J Pharmacol Exp Ther. 2020 Jan;372(1):83-94. doi: 10.1124/jpet.119.260968. Epub 2019 Nov 6. J Pharmacol Exp Ther. 2020. PMID: 31694876 Free PMC article.

7

The Effects of pH on the Structure and Bioavailability of Imidazobenzodiazepine-3-Carboxylate MIDD0301.

Roni MSR, Li G, Mikulsky BN, Knutson DE, Mian MY, Zahn NM, Cook JM, Stafford DC, Arnold LA. Roni MSR, et al. Among authors: li g. Mol Pharm. 2020 Apr 6;17(4):1182-1192. doi: 10.1021/acs.molpharmaceut.9b01210. Epub 2020 Feb 26. Mol Pharm. 2020. PMID: 32069056 Free PMC article.

8

Improved Synthesis of Anxiolytic, Anticonvulsant and Antinociceptive α2/α3-GABA(A)ergic Receptor Subtype Selective Ligands as Promising Agents to Treat Anxiety, Epilepsy, as well as Neuropathic Pain.

Li G, Golani LK, Jahan R, Rashid F, Cook JM. Li G, et al. Synthesis (Stuttg). 2018 Oct;50(20):4124-4132. doi: 10.1055/s-0037-1610211. Synthesis (Stuttg). 2018. PMID: 32773890 Free PMC article.

9

GABA_A Receptor Subtypes and the Abuse-Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators.

Berro LF, Rüedi-Bettschen D, Cook JE, Golani LK, Li G, Jahan R, Rashid F, Cook JM, Rowlett JK, Platt DM. Berro LF, et al. Among authors: li g. Alcohol Clin Exp Res. 2019 May;43(5):791-802. doi: 10.1111/acer.14000. Epub 2019 Apr 8. Alcohol Clin Exp Res. 2019. PMID: 30861153 Free PMC article.

10

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders.

Prevot TD, Li G, Cook JM, Sibille E. Prevot TD, et al. Among authors: li g. ACS Chem Neurosci. 2019 May 15;10(5):2088-2090. doi: 10.1021/acschemneuro.9b00148. Epub 2019 Mar 28. ACS Chem Neurosci. 2019. PMID: 30920790

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