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Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase.
Makni-Maalej K, Chiandotto M, Hurtado-Nedelec M, Bedouhene S, Gougerot-Pocidalo MA, Dang PM, El-Benna J. Makni-Maalej K, et al. Among authors: bedouhene s. Biochem Pharmacol. 2013 Jan 1;85(1):92-100. doi: 10.1016/j.bcp.2012.10.010. Epub 2012 Oct 22. Biochem Pharmacol. 2013. PMID: 23085266
The protein tyrosine phosphatase Lyp/PTPN22 drives TNFα-induced priming of superoxide anions production by neutrophils and arthritis.
Gardette A, Marzaioli V, Bedouhene S, Hayem G, Hurtado-Nedelec M, He Y, Dang PM, Dieudé P, Zhang ZY, Marie JC, El-Benna J. Gardette A, et al. Among authors: bedouhene s. Free Radic Biol Med. 2024 Dec 24;228:68-78. doi: 10.1016/j.freeradbiomed.2024.12.046. Online ahead of print. Free Radic Biol Med. 2024. PMID: 39724988 Free article.