Abdel-Hamid H - Search Results

1

Battle tactics against MMP-9; discovery of novel non-hydroxamate MMP-9 inhibitors endowed with PI3K/AKT signaling attenuation and caspase 3/7 activation via Ugi bis-amide synthesis.

Ayoup MS, Fouad MA, Abdel-Hamid H, Ramadan ES, Abu-Serie MM, Noby A, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2020 Jan 15;186:111875. doi: 10.1016/j.ejmech.2019.111875. Epub 2019 Nov 10. Eur J Med Chem. 2020. PMID: 31740054

2

Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators.

Salah Ayoup M, Wahby Y, Abdel-Hamid H, Ramadan ES, Teleb M, Abu-Serie MM, Noby A. Salah Ayoup M, et al. Eur J Med Chem. 2019 Apr 15;168:340-356. doi: 10.1016/j.ejmech.2019.02.051. Epub 2019 Feb 22. Eur J Med Chem. 2019. PMID: 30826510

3

Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy.

Ayoup MS, Abu-Serie MM, Abdel-Hamid H, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2021 Aug 5;220:113475. doi: 10.1016/j.ejmech.2021.113475. Epub 2021 Apr 16. Eur J Med Chem. 2021. PMID: 33901898

4

Exploration of Nitroaromatic Antibiotics via Sanger's Reagent: Synthesis, In Silico, and Antimicrobial Evaluation.

Ayoup MS, Rabee AR, Abdel-Hamid H, Harras MF, El Menofy NG, Ismail MMF. Ayoup MS, et al. ACS Omega. 2022 Feb 7;7(6):5254-5263. doi: 10.1021/acsomega.1c06383. eCollection 2022 Feb 15. ACS Omega. 2022. PMID: 35187340 Free PMC article.

5

Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications.

Fouad MA, Abdel-Hamid H, Ayoup MS. Fouad MA, et al. RSC Adv. 2020 Nov 23;10(70):42644-42681. doi: 10.1039/d0ra07501a. eCollection 2020 Nov 23. RSC Adv. 2020. PMID: 35514898 Free PMC article. Review.

6

Synthesis of a new magnetic Sulfacetamide-Ethylacetoacetate hydrazone-chitosan Schiff-base for Cr(VI) removal.

Eltaweil AS, Hashem OA, Abdel-Hamid H, Abd El-Monaem EM, Ayoup MS. Eltaweil AS, et al. Int J Biol Macromol. 2022 Dec 1;222(Pt A):1465-1475. doi: 10.1016/j.ijbiomac.2022.09.081. Epub 2022 Sep 14. Int J Biol Macromol. 2022. PMID: 36113599

7

Nature-inspired new isoindole-based Passerini adducts as efficient tumor-selective apoptotic inducers via caspase-3/7 activation.

Ayoup MS, Mansour AF, Abdel-Hamid H, Abu-Serie MM, Mohyeldin SM, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114865. doi: 10.1016/j.ejmech.2022.114865. Epub 2022 Oct 27. Eur J Med Chem. 2023. PMID: 36335743

8

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators.

Ayoup MS, Wahby Y, Abdel-Hamid H, Abu-Serie MM, Teleb M. Ayoup MS, et al. Sci Rep. 2022 Dec 27;12(1):22390. doi: 10.1038/s41598-022-26469-4. Sci Rep. 2022. PMID: 36575196 Free PMC article.

9

4-(N-Phthalimido)phenyl Isonitrile as a Novel Convertible Isocyanide Analogue with the Odorless Property as an Extra Bonus.

Ayoup MS, Mansour AF, Abdel-Hamid H. Ayoup MS, et al. ACS Omega. 2023 Jan 10;8(3):3298-3302. doi: 10.1021/acsomega.2c06884. eCollection 2023 Jan 24. ACS Omega. 2023. PMID: 36713726 Free PMC article.

10

Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential.

Ayoup MS, ElShafey MM, Abdel-Hamid H, Ghareeb DA, Abu-Serie MM, Heikal LA, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2023 Apr 5;252:115272. doi: 10.1016/j.ejmech.2023.115272. Epub 2023 Mar 13. Eur J Med Chem. 2023. PMID: 36966652 Free PMC article.

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