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Pharmacokinetic and pharmacodynamic modelling for renal function dependent urinary glucose excretion effect of ipragliflozin, a selective sodium-glucose cotransporter 2 inhibitor, both in healthy subjects and patients with type 2 diabetes mellitus.
Saito M, Kaibara A, Kadokura T, Toyoshima J, Yoshida S, Kazuta K, Ueyama E. Saito M, et al. Among authors: toyoshima j. Br J Clin Pharmacol. 2019 Aug;85(8):1808-1819. doi: 10.1111/bcp.13972. Epub 2019 Jun 20. Br J Clin Pharmacol. 2019. PMID: 31026084 Free PMC article. Clinical Trial.
Efficacy and safety of fidaxomicin for the treatment of Clostridioides (Clostridium) difficile infection in a randomized, double-blind, comparative Phase III study in Japan.
Mikamo H, Tateda K, Yanagihara K, Kusachi S, Takesue Y, Miki T, Oizumi Y, Gamo K, Hashimoto A, Toyoshima J, Kato K. Mikamo H, et al. Among authors: toyoshima j. J Infect Chemother. 2018 Sep;24(9):744-752. doi: 10.1016/j.jiac.2018.05.010. Epub 2018 Jun 19. J Infect Chemother. 2018. PMID: 29934056 Free article. Clinical Trial.
Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function.
Miyatake D, Shibata T, Toyoshima J, Kaneko Y, Oda K, Nishimura T, Katashima M, Sakaki M, Inoue K, Ito T, Uchida N, Furihata K, Urae A. Miyatake D, et al. Among authors: toyoshima j. Clin Pharmacol Drug Dev. 2020 Aug;9(6):699-708. doi: 10.1002/cpdd.751. Epub 2019 Dec 12. Clin Pharmacol Drug Dev. 2020. PMID: 31833184 Free PMC article.
Safety and Antitumor Activity of Repeated ASP3026 Administration in Japanese Patients with Solid Tumors: A Phase I Study.
Ono A, Murakami H, Seto T, Shimizu T, Watanabe S, Takeshita S, Takeda K, Toyoshima J, Nagase I, Bahceci E, Morishita M, Morita S, Fukuoka M, Nakagawa K. Ono A, et al. Among authors: toyoshima j. Drugs R D. 2021 Mar;21(1):65-78. doi: 10.1007/s40268-020-00331-2. Epub 2020 Dec 17. Drugs R D. 2021. PMID: 33331996 Free PMC article. Clinical Trial.
22 results