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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.
Tahtinen S, Tong AJ, Himmels P, Oh J, Paler-Martinez A, Kim L, Wichner S, Oei Y, McCarron MJ, Freund EC, Amir ZA, de la Cruz CC, Haley B, Blanchette C, Schartner JM, Ye W, Yadav M, Sahin U, Delamarre L, Mellman I. Tahtinen S, et al. Among authors: tong aj. Nat Immunol. 2022 Apr;23(4):532-542. doi: 10.1038/s41590-022-01160-y. Epub 2022 Mar 24. Nat Immunol. 2022. PMID: 35332327
Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2.
Aliyari SR, Ghaffari AA, Pernet O, Parvatiyar K, Wang Y, Gerami H, Tong AJ, Vergnes L, Takallou A, Zhang A, Wei X, Chilin LD, Wu Y, Semenkovich CF, Reue K, Smale ST, Lee B, Cheng G. Aliyari SR, et al. Among authors: tong aj. Acta Pharm Sin B. 2022 Apr;12(4):1624-1635. doi: 10.1016/j.apsb.2022.02.019. Epub 2022 Feb 28. Acta Pharm Sin B. 2022. PMID: 35251918 Free PMC article.
34 results