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Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease.
Di Sabatino A, Rovedatti L, Kaur R, Spencer JP, Brown JT, Morisset VD, Biancheri P, Leakey NA, Wilde JI, Scott L, Corazza GR, Lee K, Sengupta N, Knowles CH, Gunthorpe MJ, McLean PG, MacDonald TT, Kruidenier L. Di Sabatino A, et al. Among authors: macdonald tt. J Immunol. 2009 Sep 1;183(5):3454-62. doi: 10.4049/jimmunol.0802887. Epub 2009 Jul 31. J Immunol. 2009. PMID: 19648266
Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.
Docena G, Rovedatti L, Kruidenier L, Fanning A, Leakey NA, Knowles CH, Lee K, Shanahan F, Nally K, McLean PG, Di Sabatino A, MacDonald TT. Docena G, et al. Among authors: macdonald tt. Clin Exp Immunol. 2010 Oct;162(1):108-15. doi: 10.1111/j.1365-2249.2010.04203.x. Epub 2010 Aug 20. Clin Exp Immunol. 2010. PMID: 20731675 Free PMC article.
Fibroblast activation protein expression in Crohn's disease strictures.
Rovedatti L, Di Sabatino A, Knowles CH, Sengupta N, Biancheri P, Corazza GR, MacDonald TT. Rovedatti L, et al. Among authors: macdonald tt. Inflamm Bowel Dis. 2011 May;17(5):1251-3. doi: 10.1002/ibd.21446. Epub 2010 Aug 30. Inflamm Bowel Dis. 2011. PMID: 20806341 No abstract available.
The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis.
Biancheri P, Pender SL, Ammoscato F, Giuffrida P, Sampietro G, Ardizzone S, Ghanbari A, Curciarello R, Pasini A, Monteleone G, Corazza GR, Macdonald TT, Di Sabatino A. Biancheri P, et al. Among authors: macdonald tt. Fibrogenesis Tissue Repair. 2013 Jul 8;6(1):13. doi: 10.1186/1755-1536-6-13. Fibrogenesis Tissue Repair. 2013. PMID: 23834907 Free PMC article.
The Role of Cytokines in the Fibrotic Responses in Crohn's Disease.
Curciarello R, Docena GH, MacDonald TT. Curciarello R, et al. Among authors: macdonald tt. Front Med (Lausanne). 2017 Aug 7;4:126. doi: 10.3389/fmed.2017.00126. eCollection 2017. Front Med (Lausanne). 2017. PMID: 28824915 Free PMC article. Review.
What's the next best cytokine target in IBD?
MacDonald TT, Biancheri P, Sarra M, Monteleone G. MacDonald TT, et al. Inflamm Bowel Dis. 2012 Nov;18(11):2180-9. doi: 10.1002/ibd.22967. Epub 2012 Apr 16. Inflamm Bowel Dis. 2012. PMID: 22508526 Review.
365 results