Huang W - Search Results

1

Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis.

Qin K, Shi W, Zhao L, Li M, Tang Y, Faridoon, Jiang B, Tang F, Huang W. Qin K, et al. Among authors: huang w. Bioorg Chem. 2020 Jan;94:103391. doi: 10.1016/j.bioorg.2019.103391. Epub 2019 Nov 9. Bioorg Chem. 2020. PMID: 31761409

2

One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates.

Tang F, Yang Y, Tang Y, Tang S, Yang L, Sun B, Jiang B, Dong J, Liu H, Huang M, Geng MY, Huang W. Tang F, et al. Among authors: huang m, huang w. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518. doi: 10.1039/c6ob01751g. Org Biomol Chem. 2016. PMID: 27714198

3

Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates.

Tang F, Wang LX, Huang W. Tang F, et al. Among authors: huang w. Nat Protoc. 2017 Aug;12(8):1702-1721. doi: 10.1038/nprot.2017.058. Epub 2017 Jul 27. Nat Protoc. 2017. PMID: 28749929 Free PMC article.

4

Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control.

Tang Y, Tang F, Yang Y, Zhao L, Zhou H, Dong J, Huang W. Tang Y, et al. Among authors: huang w. Sci Rep. 2017 Aug 10;7(1):7763. doi: 10.1038/s41598-017-08151-2. Sci Rep. 2017. PMID: 28798339 Free PMC article.

5

Homogeneous Antibody-Drug Conjugates via Glycoengineering.

Tang F, Shi W, Huang W. Tang F, et al. Among authors: huang w. Methods Mol Biol. 2019;2033:221-238. doi: 10.1007/978-1-4939-9654-4_15. Methods Mol Biol. 2019. PMID: 31332757

6

Glycoengineering and glycosite-specific labeling of serum IgGs from various species.

Guo W, Tang F, Qin K, Zhou M, Le Z, Huang W. Guo W, et al. Among authors: huang w. Carbohydr Res. 2017 Jun 29;446-447:32-39. doi: 10.1016/j.carres.2017.05.001. Epub 2017 May 4. Carbohydr Res. 2017. PMID: 28494315

7

One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling.

Zhao K, Tang F, Shi W, Hong H, Zhou Z, Huang W, Wu Z. Zhao K, et al. Among authors: huang w. Bioorg Chem. 2019 Oct;91:103114. doi: 10.1016/j.bioorg.2019.103114. Epub 2019 Jul 12. Bioorg Chem. 2019. PMID: 31336307

8

A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide.

Hu Y, Zou X, Shi W, Ma C, Chen F, Li J, Jiao S, Pan G, Lan L, Huang W, Tang F, Zhang F. Hu Y, et al. Among authors: huang w. Bioorg Med Chem Lett. 2021 Jun 15;42:128027. doi: 10.1016/j.bmcl.2021.128027. Epub 2021 Apr 9. Bioorg Med Chem Lett. 2021. PMID: 33839255

9

Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates.

Shi W, Chen F, Zou X, Jiao S, Wang S, Hu Y, Lan L, Tang F, Huang W. Shi W, et al. Among authors: huang w. Bioorg Med Chem Lett. 2021 Aug 1;45:128122. doi: 10.1016/j.bmcl.2021.128122. Epub 2021 May 17. Bioorg Med Chem Lett. 2021. PMID: 34015504

10

One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates.

Shi W, Li W, Zhang J, Li T, Song Y, Zeng Y, Dong Q, Lin Z, Gong L, Fan S, Tang F, Huang W. Shi W, et al. Among authors: huang w. Acta Pharm Sin B. 2022 May;12(5):2417-2428. doi: 10.1016/j.apsb.2021.12.013. Epub 2021 Dec 24. Acta Pharm Sin B. 2022. PMID: 35646546 Free PMC article.

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