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LFA-1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune proinflammatory phenotypes.
Noor S, Sun MS, Vanderwall AG, Havard MA, Sanchez JE, Harris NW, Nysus MV, Norenberg JP, West HT, Wagner CR, Jantzie LL, Mellios N, Milligan ED. Noor S, et al. Among authors: nysus mv. Neuroimmunol Neuroinflamm. 2019;6:10. doi: 10.20517/2347-8659.2019.18. Epub 2019 Jul 22. Neuroimmunol Neuroinflamm. 2019. PMID: 31763376 Free PMC article.
The LFA-1 antagonist BIRT377 reverses neuropathic pain in prenatal alcohol-exposed female rats via actions on peripheral and central neuroimmune function in discrete pain-relevant tissue regions.
Noor S, Sanchez JJ, Sun MS, Pervin Z, Sanchez JE, Havard MA, Epler LT, Nysus MV, Norenberg JP, Wagner CR, Davies S, Wagner JL, Savage DD, Jantzie LL, Mellios N, Milligan ED. Noor S, et al. Among authors: nysus mv. Brain Behav Immun. 2020 Jul;87:339-358. doi: 10.1016/j.bbi.2020.01.002. Epub 2020 Jan 7. Brain Behav Immun. 2020. PMID: 31918004 Free PMC article.
111In-DANBIRT In Vivo Molecular Imaging of Inflammatory Cells in Atherosclerosis.
Mota R, Campen MJ, Cuellar ME, Garver WS, Hesterman J, Qutaish M, Daniels T, Nysus M, Wagner CR, Norenberg JP. Mota R, et al. Contrast Media Mol Imaging. 2018 Nov 13;2018:6508724. doi: 10.1155/2018/6508724. eCollection 2018. Contrast Media Mol Imaging. 2018. PMID: 30538613 Free PMC article.
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.
Matthijssens F, Sharma ND, Nysus M, Nickl CK, Kang H, Perez DR, Lintermans B, Van Loocke W, Roels J, Peirs S, Demoen L, Pieters T, Reunes L, Lammens T, De Moerloose B, Van Nieuwerburgh F, Deforce DL, Cheung LC, Kotecha RS, Risseeuw MD, Van Calenbergh S, Takarada T, Yoneda Y, van Delft FW, Lock RB, Merkley SD, Chigaev A, Sklar LA, Mullighan CG, Loh ML, Winter SS, Hunger SP, Goossens S, Castillo EF, Ornatowski W, Van Vlierberghe P, Matlawska-Wasowska K. Matthijssens F, et al. J Clin Invest. 2021 Mar 15;131(6):e141566. doi: 10.1172/JCI141566. J Clin Invest. 2021. PMID: 33555272 Free PMC article.
Prenatal alcohol exposure promotes NLRP3 inflammasome-dependent immune actions following morphine treatment and paradoxically prolongs nerve injury-induced pathological pain in female mice.
Noor S, Sun MS, Pasmay AA, Pritha AN, Ruffaner-Hanson CD, Nysus MV, Jimenez DC, Murphy M, Savage DD, Valenzuela CF, Milligan ED. Noor S, et al. Among authors: nysus mv. Alcohol Clin Exp Res (Hoboken). 2023 Dec;47(12):2262-2277. doi: 10.1111/acer.15214. Epub 2023 Nov 5. Alcohol Clin Exp Res (Hoboken). 2023. PMID: 38151779 Free PMC article.