Kaniyappan S - Search Results

1

The Plasma Factor XIII Heterotetrameric Complex Structure: Unexpected Unequal Pairing within a Symmetric Complex.

Singh S, Nazabal A, Kaniyappan S, Pellequer JL, Wolberg AS, Imhof D, Oldenburg J, Biswas A. Singh S, et al. Among authors: kaniyappan s. Biomolecules. 2019 Nov 21;9(12):765. doi: 10.3390/biom9120765. Biomolecules. 2019. PMID: 31766577 Free PMC article.

2

Disruption of Structural Disulfides of Coagulation FXIII-B Subunit; Functional Implications for a Rare Bleeding Disorder.

Singh S, Akhter MS, Dodt J, Sharma A, Kaniyappan S, Yadegari H, Ivaskevicius V, Oldenburg J, Biswas A. Singh S, et al. Among authors: kaniyappan s. Int J Mol Sci. 2019 Apr 22;20(8):1956. doi: 10.3390/ijms20081956. Int J Mol Sci. 2019. PMID: 31013569 Free PMC article.

3

Purification and Characterization of Low-n Tau Oligomers.

Kaniyappan S, Chandupatla RR, Mandelkow E. Kaniyappan S, et al. Methods Mol Biol. 2018;1779:99-111. doi: 10.1007/978-1-4939-7816-8_8. Methods Mol Biol. 2018. PMID: 29886530

4

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.

Kaniyappan S, Tepper K, Biernat J, Chandupatla RR, Hübschmann S, Irsen S, Bicher S, Klatt C, Mandelkow EM, Mandelkow E. Kaniyappan S, et al. Mol Neurodegener. 2020 Jul 16;15(1):39. doi: 10.1186/s13024-020-00389-1. Mol Neurodegener. 2020. PMID: 32677995 Free PMC article.

5

The release and trans-synaptic transmission of Tau via exosomes.

Wang Y, Balaji V, Kaniyappan S, Krüger L, Irsen S, Tepper K, Chandupatla R, Maetzler W, Schneider A, Mandelkow E, Mandelkow EM. Wang Y, et al. Among authors: kaniyappan s. Mol Neurodegener. 2017 Jan 13;12(1):5. doi: 10.1186/s13024-016-0143-y. Mol Neurodegener. 2017. PMID: 28086931 Free PMC article.

6

Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability.

Kaniyappan S, Chandupatla RR, Mandelkow EM, Mandelkow E. Kaniyappan S, et al. Alzheimers Dement. 2017 Nov;13(11):1270-1291. doi: 10.1016/j.jalz.2017.04.002. Epub 2017 May 18. Alzheimers Dement. 2017. PMID: 28528849

7

Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems.

Balaji V, Kaniyappan S, Mandelkow E, Wang Y, Mandelkow EM. Balaji V, et al. Among authors: kaniyappan s. Autophagy. 2018;14(12):2139-2154. doi: 10.1080/15548627.2018.1509607. Epub 2018 Sep 13. Autophagy. 2018. PMID: 30145931 Free PMC article.

8

Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment.

Pir GJ, Choudhary B, Kaniyappan S, Chandupatla RR, Mandelkow E, Mandelkow EM, Wang Y. Pir GJ, et al. Among authors: kaniyappan s. Mol Neurobiol. 2019 May;56(5):3751-3767. doi: 10.1007/s12035-018-1326-z. Epub 2018 Sep 8. Mol Neurobiol. 2019. PMID: 30196394 Free PMC article.

9

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications.

Drepper F, Biernat J, Kaniyappan S, Meyer HE, Mandelkow EM, Warscheid B, Mandelkow E. Drepper F, et al. Among authors: kaniyappan s. J Biol Chem. 2020 Dec 25;295(52):18213-18225. doi: 10.1074/jbc.RA120.015882. Epub 2020 Oct 26. J Biol Chem. 2020. PMID: 33106314 Free PMC article.

10

Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes.

Chandupatla RR, Flatley A, Feederle R, Mandelkow EM, Kaniyappan S. Chandupatla RR, et al. Among authors: kaniyappan s. Alzheimers Dement (N Y). 2020 Oct 28;6(1):e12097. doi: 10.1002/trc2.12097. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 33145390 Free PMC article.

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