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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, Bedi KC Jr, Rame JE, Bogner-Strauss JG, Mesaros C, Sidoli S, Wellen KE, Snyder NW. Trefely S, et al. Among authors: singh j. Mol Cell. 2022 Jan 20;82(2):447-462.e6. doi: 10.1016/j.molcel.2021.11.006. Epub 2021 Dec 1. Mol Cell. 2022. PMID: 34856123 Free PMC article.
Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species.
Doan MT, Neinast MD, Varner EL, Bedi KC Jr, Bartee D, Jiang H, Trefely S, Xu P, Singh JP, Jang C, Rame JE, Brady DC, Meier JL, Marguiles KB, Arany Z, Snyder NW. Doan MT, et al. Among authors: singh jp. J Lipid Res. 2022 Jun;63(6):100224. doi: 10.1016/j.jlr.2022.100224. Epub 2022 May 11. J Lipid Res. 2022. PMID: 35568254 Free PMC article.
Basic Science and Pathogenesis.
Wang N, Parsons TM, Ren Y, Pan Y, Starling SC, Muolokwu C, Singh J, Kanekiyo T. Wang N, et al. Among authors: singh j. Alzheimers Dement. 2024 Dec;20 Suppl 1:e088234. doi: 10.1002/alz.088234. Alzheimers Dement. 2024. PMID: 39751428
Basic Science and Pathogenesis.
Sanchez-Molina P, Brownell D, Pratapa A, Nikulina N, Cheikh BB, Singh J, Bogachuk A, Chiot A, Chin G, Emberley K, Crotti A, Woltjer R, Svara F, Braubach O, Ajami B. Sanchez-Molina P, et al. Among authors: singh j. Alzheimers Dement. 2024 Dec;20 Suppl 1:e088495. doi: 10.1002/alz.088495. Alzheimers Dement. 2024. PMID: 39751415
Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons.
Dvorak NM, Wadsworth PA, Aquino-Miranda G, Wang P, Engelke DS, Zhou J, Nguyen N, Singh AK, Aceto G, Haghighijoo Z, Smith II, Goode N, Zhou M, Avchalumov Y, Troendle EP, Tapia CM, Chen H, Powell RT, Baumgartner TJ, Singh J, Koff L, Di Re J, Wadsworth AE, Marosi M, Azar MR, Elias K, Lehmann P, Mármol Contreras YM, Shah P, Gutierrez H, Green TA, Ulmschneider MB, D'Ascenzo M, Stephan C, Cui G, Do Monte FH, Zhou J, Laezza F. Dvorak NM, et al. Among authors: singh j. Nat Commun. 2025 Jan 2;16(1):110. doi: 10.1038/s41467-024-55554-7. Nat Commun. 2025. PMID: 39747162 Free article.
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled trial.
Bosma KJ, Lafreniere-Roula M, Jiang A, Heath A, Ouyang Y, Wade K, Hu P, Burns KEA, Martin CM, Skrobik Y, Mulligan S, Thorpe KE, Brochard L; members of the Canadian Critical Care Trials Group and the REVA Network. Bosma KJ, et al. Trials. 2024 Dec 30;25(1):855. doi: 10.1186/s13063-024-08669-7. Trials. 2024. PMID: 39736673 Free PMC article.
9,050 results