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A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation.
Hofman ZLM, Clark CC, Sanrattana W, Nosairi A, Parr NMJ, Živkovic M, Krause K, Mahnke NA, Scheffel J, Hack CE, Maurer M, de Maat S, Maas C. Hofman ZLM, et al. Among authors: scheffel j. J Biol Chem. 2020 Jan 10;295(2):363-374. doi: 10.1074/jbc.RA119.009788. Epub 2019 Nov 26. J Biol Chem. 2020. PMID: 31771982 Free PMC article.
The role of mast cells in autoinflammation.
Bonnekoh H, Scheffel J, Kambe N, Krause K. Bonnekoh H, et al. Among authors: scheffel j. Immunol Rev. 2018 Mar;282(1):265-275. doi: 10.1111/imr.12633. Immunol Rev. 2018. PMID: 29431217 Review.
Immunoglobulin E-Mediated Autoimmunity.
Maurer M, Altrichter S, Schmetzer O, Scheffel J, Church MK, Metz M. Maurer M, et al. Among authors: scheffel j. Front Immunol. 2018 Apr 9;9:689. doi: 10.3389/fimmu.2018.00689. eCollection 2018. Front Immunol. 2018. PMID: 29686678 Free PMC article. Review.
The complex role of mast cells in fungal infections.
Jiao Q, Luo Y, Scheffel J, Zhao Z, Maurer M. Jiao Q, et al. Among authors: scheffel j. Exp Dermatol. 2019 Jul;28(7):749-755. doi: 10.1111/exd.13907. Epub 2019 Mar 22. Exp Dermatol. 2019. PMID: 30801834 Review.
Chymase-Cre; Mcl-1fl/fl Mice Exhibit Reduced Numbers of Mucosal Mast Cells.
Luo Y, Meyer N, Jiao Q, Scheffel J, Zimmermann C, Metz M, Zenclussen A, Maurer M, Siebenhaar F. Luo Y, et al. Among authors: scheffel j. Front Immunol. 2019 Oct 15;10:2399. doi: 10.3389/fimmu.2019.02399. eCollection 2019. Front Immunol. 2019. PMID: 31681290 Free PMC article.
122 results