Pohler E - Search Results

1

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity.

Martinez-Fabregas J, Wilmes S, Wang L, Hafer M, Pohler E, Lokau J, Garbers C, Cozzani A, Fyfe PK, Piehler J, Kazemian M, Mitra S, Moraga I. Martinez-Fabregas J, et al. Among authors: pohler e. Elife. 2019 Nov 27;8:e49314. doi: 10.7554/eLife.49314. Elife. 2019. PMID: 31774398 Free PMC article.

2

Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses.

Gorby C, Sotolongo Bellón J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, Moraga I. Gorby C, et al. Among authors: pohler e. Sci Signal. 2020 Sep 15;13(649):eabc0653. doi: 10.1126/scisignal.abc0653. Sci Signal. 2020. PMID: 32934073 Free PMC article.

3

CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci.

Martinez-Fabregas J, Wang L, Pohler E, Cozzani A, Wilmes S, Kazemian M, Mitra S, Moraga I. Martinez-Fabregas J, et al. Among authors: pohler e. Cell Rep. 2020 Dec 22;33(12):108545. doi: 10.1016/j.celrep.2020.108545. Cell Rep. 2020. PMID: 33357429 Free PMC article.

4

Identifying cytokine signaling signatures in primary human Th-1 cells by phospho-proteomics analysis.

Martinez-Fabregas J, Pohler E, Moraga I. Martinez-Fabregas J, et al. Among authors: pohler e. STAR Protoc. 2021 Mar 31;2(2):100417. doi: 10.1016/j.xpro.2021.100417. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 33870224 Free PMC article.

5

Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.

Wilmes S, Jeffrey PA, Martinez-Fabregas J, Hafer M, Fyfe PK, Pohler E, Gaggero S, López-García M, Lythe G, Taylor C, Guerrier T, Launay D, Mitra S, Piehler J, Molina-París C, Moraga I. Wilmes S, et al. Among authors: pohler e. Elife. 2021 Apr 19;10:e66014. doi: 10.7554/eLife.66014. Elife. 2021. PMID: 33871355 Free PMC article.

6

Molecular and cellular factors determining the functional pleiotropy of cytokines.

McFarlane A, Pohler E, Moraga I. McFarlane A, et al. Among authors: pohler e. FEBS J. 2023 May;290(10):2525-2552. doi: 10.1111/febs.16420. Epub 2022 Mar 14. FEBS J. 2023. PMID: 35246947 Free PMC article. Review.

7

The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury.

Darragh J, Hunter M, Pohler E, Nelson L, Dillon JF, Nenutil R, Vojtesek B, Ross PE, Kernohan N, Hupp TR. Darragh J, et al. Among authors: pohler e. FEBS J. 2006 May;273(9):1930-47. doi: 10.1111/j.1742-4658.2006.05206.x. FEBS J. 2006. PMID: 16640557 Free article.

8

Heterozygous mutations in AAGAB cause type 1 punctate palmoplantar keratoderma with evidence for increased growth factor signaling.

Pöhler E, Zamiri M, Harkins CP, Salas-Alanis JC, Perkins W, Smith FJD, Irwin McLean WH, Brown SJ. Pöhler E, et al. J Invest Dermatol. 2013 Dec;133(12):2805-2808. doi: 10.1038/jid.2013.243. Epub 2013 Jun 6. J Invest Dermatol. 2013. PMID: 23743648 Free PMC article. No abstract available.

9

The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage.

Pohler E, Craig AL, Cotton J, Lawrie L, Dillon JF, Ross P, Kernohan N, Hupp TR. Pohler E, et al. Mol Cell Proteomics. 2004 Jun;3(6):534-47. doi: 10.1074/mcp.M300089-MCP200. Epub 2004 Feb 15. Mol Cell Proteomics. 2004. PMID: 14967811 Free article.

10

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.

Burch LR, Scott M, Pohler E, Meek D, Hupp T. Burch LR, et al. Among authors: pohler e. J Mol Biol. 2004 Mar 12;337(1):115-28. doi: 10.1016/j.jmb.2003.10.081. J Mol Biol. 2004. PMID: 15001356

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