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A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z. Kesselring L, et al. Among authors: wang y. Nucleic Acids Res. 2020 Jan 10;48(1):316-331. doi: 10.1093/nar/gkz1119. Nucleic Acids Res. 2020. PMID: 31777924 Free PMC article.
Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition.
Wang Y, Pryputniewicz-Dobrinska D, Nagy EÉ, Kaufman CD, Singh M, Yant S, Wang J, Dalda A, Kay MA, Ivics Z, Izsvák Z. Wang Y, et al. Among authors: wang j. Nucleic Acids Res. 2017 Jan 9;45(1):311-326. doi: 10.1093/nar/gkw1164. Epub 2016 Dec 1. Nucleic Acids Res. 2017. PMID: 27913727 Free PMC article.
Advances and applications in single-cell and spatial genomics.
Wang J, Ye F, Chai H, Jiang Y, Wang T, Ran X, Xia Q, Xu Z, Fu Y, Zhang G, Wu H, Guo G, Guo H, Ruan Y, Wang Y, Xing D, Xu X, Zhang Z. Wang J, et al. Among authors: wang y. Sci China Life Sci. 2024 Dec 20. doi: 10.1007/s11427-024-2770-x. Online ahead of print. Sci China Life Sci. 2024. PMID: 39792333 Review.
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